(4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine

Base Information

• Chemical Name: (4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine
• CAS No.: 1365842-31-4
• Molecular Formula: C₂₆H₃₆N₂
• Molecular Weight: 376.585
• Mol file: 1365842-31-4.mol

Synonyms:(4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine

Chemical Property of (4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine

There total 3 articles about (4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

(E,E)-N1,N2-bis(2,4,6-trimethylphenyl)ethane-1,2-diimine (56222-36-7) + allylmagnesium bromide (2622-05-1) → (4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine (1365842-31-4)

Guidance literature:

(E,E)-N¹,N²-bis(2,4,6-trimethylphenyl)ethane-1,2-diimine; allylmagnesium bromide; In tetrahydrofuran; at -94 - 20 ℃; for 16h; Schlenk technique;

With ammonium chloride; In water; at 0 ℃;

DOI:10.1002/ejoc.201402649

Reference yield: 54.0%

allylmagnesium bromide (2622-05-1) + N,N'-bis(2,4,6-trimethylphenyl)ethanediimine (56222-36-7) → (4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine (1365842-31-4)

Guidance literature:

In tetrahydrofuran; at -94 - 20 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejoc.201402649

Reference yield:

2,4,6-trimethylaniline (88-05-1) → (4R,5S)-N,N'-dimesitylocta-1,7-diene-4,5-diamine (1365842-31-4)

Guidance literature:

Multi-step reaction with 2 steps

1: water; isopropyl alcohol / 20 h / 20 - 60 °C

2: tetrahydrofuran / 16 h / -94 - 20 °C / Schlenk technique; Inert atmosphere

In tetrahydrofuran; water; isopropyl alcohol;

DOI:10.1002/ejoc.201402649

upstream raw materials:

(E,E)-N¹,N²-bis(2,4,6-trimethylphenyl)ethane-1,2-diimine

allylmagnesium bromide

N,N'-bis(2,4,6-trimethylphenyl)ethanediimine

2,4,6-trimethylaniline

Downstream raw materials:

(1R,2S)-N₁,N₂-dimesitylcyclohex-4-ene-1,2-diamine

1,3-dimesityl-4,5-bis[3-(triethoxysilyl)propyl]-4,5-dihydroimidazol-1H-ium chloride

(4S,5R)-4,5-diallyl-1,3-dimesityl-4,5-dihydro-1H-imidazol-3-ium chloride