2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

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Chemical Name:2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole
CAS No.:667940-38-7
Molecular Formula:C₄₁H₅₂N₆O₃S
Molecular Weight:708.968
Hs Code.:

2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

Synonyms:2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

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Chemical Property of 2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

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Technology Process of 2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

There total 7 articles about 2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 150281-47-3
4-pyrrolidin-3-yl-pyridine

: 667940-66-1
C₃₂H₄₂N₄O₃S₂

: 667940-38-7
C₄₁H₅₂N₆O₃S

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2007.09.099

Reference yield: 55.0%

: 150281-47-3
4-pyrrolidin-3-yl-pyridine

: 667940-66-1
C₃₂H₄₂N₄O₃S₂

: 667940-38-7
2-(1,1-dimethyl-2-oxo-2-azabicyclo[2.2.1] heptan-7-ylethyl)-4-[1S-methyl-2-(N'-isopropoxycarbonyl-3-pyrid-4-yl-pyrrolidin-1-ylcarboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

Guidance literature:: With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 24h;

Reference yield: 55.0%

: 150281-47-3
4-pyrrolidin-3-yl-pyridine

: 667940-66-1
C₃₂H₄₂N₄O₃S₂

: 667940-38-7
2-(1,1-dimethyl-2-oxo-2-(7-azabicyclo[2.2.1]heptan-7-yl)ethyl)-4-[(1S)-1-methyl-2-(N'-isopropoxycarbonyl-3-pyridin-4-yl-pyrrolidin-1-yl-carboximidamido)ethyl]-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrole

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 24.25h;