N-(2,6-dimethoxyphenyl)-N-phenylacetamide

Base Information

Chemical Name:N-(2,6-dimethoxyphenyl)-N-phenylacetamide
CAS No.:131157-27-2
Molecular Formula:C₁₆H₁₇NO₃
Molecular Weight:271.316
Hs Code.:
DSSTox Substance ID:DTXSID701272354

Synonyms:N-(2,6-dimethoxyphenyl)-N-phenylacetamide;DTXSID701272354;131157-27-2

Suppliers and Price of N-(2,6-dimethoxyphenyl)-N-phenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2,6-dimethoxyphenyl)-N-phenylacetamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:271.12084340
Heavy Atom Count:20
Complexity:303

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)N(C1=CC=CC=C1)C2=C(C=CC=C2OC)OC

Technology Process of N-(2,6-dimethoxyphenyl)-N-phenylacetamide

There total 3 articles about N-(2,6-dimethoxyphenyl)-N-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 108-86-1,52753-63-6
bromobenzene

: 131157-26-1
N-(2,6-dimethoxyphenyl)acetamide

: 131157-27-2
2,6-Dimethoxy-N-phenylacetanilide

Guidance literature:: With iodine; copper; potassium carbonate; In nitrobenzene; for 10h; Heating;
DOI:10.1248/cpb.38.2118

Reference yield: 3.2%

: 16932-45-9
1-bromo-2,6-dimethoxybenzene

: 103-84-4
Acetanilid

: 131157-27-2
2,6-Dimethoxy-N-phenylacetanilide

Guidance literature:: With iodine; copper; potassium carbonate; In nitrobenzene; for 24h; Heating;
DOI:10.1248/cpb.38.2118

Reference yield:

: 2734-70-5
2,6-dimethoxyaniline

: 131157-27-2
2,6-Dimethoxy-N-phenylacetanilide

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / 1.67 h / Ambient temperature

2: 83 percent / K₂CO₃, Cu powder, iodine / nitrobenzene / 10 h / Heating

With iodine; copper; potassium carbonate; In nitrobenzene;
DOI:10.1248/cpb.38.2118