(Z,E)-1-Chloro-1-fluoro-2-phenethylethene

Base Information

• Chemical Name: (Z,E)-1-Chloro-1-fluoro-2-phenethylethene
• CAS No.: 260262-16-6
• Molecular Formula: C₁₀H₁₀ClF
• Molecular Weight: 184.641
• Mol file: 260262-16-6.mol

Synonyms:(Z,E)-1-Chloro-1-fluoro-2-phenethylethene

Chemical Property of (Z,E)-1-Chloro-1-fluoro-2-phenethylethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z,E)-1-Chloro-1-fluoro-2-phenethylethene

There total 1 articles about (Z,E)-1-Chloro-1-fluoro-2-phenethylethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenyl-propionaldehyde (104-53-0) + trichlorofluoromethane (75-69-4) → (Z,E)-1-Chloro-1-fluoro-2-phenethylethene (260262-16-6)

Guidance literature:

With triphenylphosphine; zinc; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1016/S0040-4039(98)02589-1

Reference yield: 83.0%

(Z,E)-1-Chloro-1-fluoro-2-phenethylethene (260262-16-6) + phenylboronic acid (98-80-6) → C16H15F

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; benzene; for 24h; Heating;

DOI:10.1016/S0040-4039(98)02589-1

Reference yield:

(Z,E)-1-Chloro-1-fluoro-2-phenethylethene (260262-16-6) + phenylboronic acid (98-80-6) → (E)-1,4-diphenyl-1-fluoro-1-butene (140137-78-6) + (Z)-1,4-diphenyl-1-fluoro-1-butene (140137-77-5)

Guidance literature:

With water; sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; for 24h; Title compound not separated from byproducts; Heating;

DOI:10.1016/S0022-1139(99)00172-4

upstream raw materials:

3-phenyl-propionaldehyde

trichlorofluoromethane

Downstream raw materials:

(E)-1,4-diphenyl-1-fluoro-1-butene

(Z)-1,4-diphenyl-1-fluoro-1-butene