9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline

Base Information

• Chemical Name: 9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline
• CAS No.: 85202-97-7
• Molecular Formula: C₁₉H₂₃N₃O
• Molecular Weight: 309.411
• Mol file: 85202-97-7.mol

Synonyms:9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline

Chemical Property of 9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline

There total 1 articles about 9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dimethyl-4-tert-butylphenol (879-97-0) + 1-azido-2-(bromomethyl)benzene (31553-17-0) → o-azidobenzyl 2,6-dimethyl-4-tert-butylphenyl ether + 6-(o-azidobenzyl)-2,6-dimethyl-4-tert-butyl-2,4-cyclohexadien-1-one + 9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline (85202-97-7)

Guidance literature:

With sodium methylate; Yield given. Multistep reaction. Title compound not separated from byproducts; 1.) benzene, room temperature, 18 h, 2.) 0-5 deg C, 4 d;

DOI:10.1021/ja00348a051

Reference yield: 85.0%

methanol (67-56-1) + 9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline (85202-97-7) → 3-[2-(4-tert-Butyl-2-methyl-pyrrol-1-yl)-phenyl]-2-methyl-propionic acid methyl ester (85203-04-9)

Guidance literature:

In tetrahydrofuran; for 1h; Irradiation;

DOI:10.1021/ja00348a051

Reference yield:

9a-tert-butyl-6a,8-dimethyl-5,6,6a,7,9a,9b-hexahydro-7-oxo-4H-1,2,3-triazolo<4,5,1-ij>benzquinoline (85202-97-7) → 3-[2-(4-tert-Butyl-2-methyl-pyrrol-1-yl)-phenyl]-2-methyl-propionic acid methyl ester (85203-04-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / benzene; decahydronaphthalene / 0.08 h / 150 °C

2: 37 percent / tetrahydrofuran / 1 h / Irradiation

In tetrahydrofuran; decalin; benzene;

DOI:10.1021/ja00348a051

upstream raw materials:

2,6-dimethyl-4-tert-butylphenol

1-azido-2-(bromomethyl)benzene

Downstream raw materials:

3-[2-(4-tert-Butyl-2-methyl-pyrrol-1-yl)-phenyl]-2-methyl-propionic acid methyl ester