2,5-dimethoxyterephthaloyl dichloride

Base Information

• Chemical Name: 2,5-dimethoxyterephthaloyl dichloride
• CAS No.: 56486-55-6
• Molecular Formula: C₁₀H₈Cl₂O₄
• Molecular Weight: 263.077
• Mol file: 56486-55-6.mol

Synonyms:2,5-dimethoxyterephthaloyl dichloride

Chemical Property of 2,5-dimethoxyterephthaloyl dichloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-dimethoxyterephthaloyl dichloride

There total 3 articles about 2,5-dimethoxyterephthaloyl dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethoxyterephthalic acid (21004-11-5) → 2,5-dimethoxyterephthaloyl dichloride (56486-55-6)

Guidance literature:

With thionyl chloride;

DOI:10.1007/BF03343817

Reference yield:

2,5-dimethoxyterephthalic acid dimethyl ester (21004-12-6) → 2,5-dimethoxyterephthaloyl dichloride (56486-55-6)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium hydroxide monohydrate; water / tetrahydrofuran / 4 h / Inert atmosphere; Reflux

2: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 0 °C / Inert atmosphere; Reflux; Schlenk technique

With thionyl chloride; lithium hydroxide monohydrate; water; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;

DOI:10.1002/asia.201801619

Reference yield:

diethyl-2,5-dimethoxy-1,4-benzenedicarboxylate (173267-23-7) → 2,5-dimethoxyterephthaloyl dichloride (56486-55-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / KOH / ethane-1,2-diol / 100 °C

2: PCl₅ / Heating

With potassium hydroxide; phosphorus pentachloride; In ethylene glycol;

DOI:10.1039/b108728m

upstream raw materials:

2,5-dimethoxyterephthalic acid

diethyl-2,5-dimethoxy-1,4-benzenedicarboxylate

2,5-dimethoxyterephthalic acid dimethyl ester

Downstream raw materials:

C₉₀H₁₀₂N₁₂O₂₂

1,4-bis(5'-(pyridin-2-yl)-1'H-1',2',4'-triazol-3'-yl)-2,5-dimethoxybenzene

bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide

1,4-bis(acylpyridin-2'-ylamidrazone)-2,5-dimethoxybenzene

Refernces

• 1、 Lautrette, Guillaume,Kauffmann, Brice,Ferrand, Yann,Aube, Christophe,Chandramouli, Nagula,Dubreuil, Didier,Huc, Ivan. "Structure elucidation of host-guest complexes of tartaric and malic acids by quasi-racemic crystallography". . p. 11517 - 11520. Retrieved 2013.
• 2、 Sebaoun, Laure,Maurizot, Victor,Granier, Thierry,Kauffmann, Brice,Huc, Ivan. "Aromatic oligoamide β-sheet foldamers". supporting information. p. 2168 - 2174. Retrieved 2014/03/21.