bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide

Base Information

• Chemical Name: bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide
• CAS No.: 906072-82-0
• Molecular Formula: C₇₄H₉₂N₄O₁₆P₂
• Molecular Weight: 1355.51
• Mol file: 906072-82-0.mol

Synonyms:bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide

Chemical Property of bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide

There total 8 articles about bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphoric acid 2,2-diphenyl-ethyl ester bis-(4-nitro-phenyl) ester (906072-79-5) → bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide (906072-82-0)

Guidance literature:

Multi-step reaction with 3 steps

1: DBU / toluene

2: trifluoroacetic acid / CH₂Cl₂ / 0.33 h

3: triethylamine / CHCl₃ / 3 h

With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; trifluoroacetic acid; In dichloromethane; chloroform; toluene;

DOI:10.1021/ja0619253

Reference yield:

12-(tert-butylcarbamoyl)dodecyl-4-nitrophenyl-2,2-diphenylethyl phosphate (906072-85-3) → bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide (906072-82-0)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / CH₂Cl₂ / 0.33 h

2: triethylamine / CHCl₃ / 3 h

With triethylamine; trifluoroacetic acid; In dichloromethane; chloroform;

DOI:10.1021/ja0619253

Reference yield:

tris(p-nitrophenyl)phosphate (3871-20-3) → bis-N,N-(p-nitrophenyl-2,2-diphenylethyl-12-aminododecyl phosphate)-2,5-dimethoxyterephthalamide (906072-82-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / DBU / CHCl₃ / 3 h

2: DBU / toluene

3: trifluoroacetic acid / CH₂Cl₂ / 0.33 h

4: triethylamine / CHCl₃ / 3 h

With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; trifluoroacetic acid; In dichloromethane; chloroform; toluene;

DOI:10.1021/ja0619253

upstream raw materials:

2,5-dimethoxyterephthaloyl dichloride

phosphoric acid 2,2-diphenyl-ethyl ester bis-(4-nitro-phenyl) ester

12-(tert-butylcarbamoyl)dodecyl-4-nitrophenyl-2,2-diphenylethyl phosphate

tris(p-nitrophenyl)phosphate

Refernces