N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide

Base Information

Chemical Name:N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide
CAS No.:1335113-61-5
Molecular Formula:C₁₇H₁₅BrF₃NO₂
Molecular Weight:402.211
Hs Code.:

Synonyms:N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide

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Technology Process of N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide

There total 1 articles about N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1206913-01-0
N-(2-bromophenyl)-N-methyl-2-oxo-2-(4-(trifluoromethyl)phenyl)acetamide

: 75-16-1
methylmagnesium bromide

: 1335113-61-5
N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide

Guidance literature:: In diethyl ether; for 3h; Inert atmosphere;
DOI:10.1039/c1cc14209g

Reference yield: 77.0%

: 1335113-61-5
N-(2-bromophenyl)-2-hydroxy-N-methyl-2-(4-(trifluoromethyl)phenyl)propanamide

: 1335113-72-8
2,4-dimethyl-2-(4-(trifluoromethyl)phenyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

Guidance literature:: With caesium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate; In toluene; at 80 ℃; for 16h; Inert atmosphere;
DOI:10.1039/c1cc14209g