5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

Base Information

Chemical Name:5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one
CAS No.:884305-07-1
Molecular Formula:C₂₁H₁₉ClN₄O₂S
Molecular Weight:426.926
Hs Code.:

Synonyms:5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

Suppliers and Price of 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
KetoZiprasidone
10mg
$ 415.00

ChemScene
KetoZiprasidone
5mg
$ 350.00

ChemScene
KetoZiprasidone
1mg
$ 120.00

Total 3 raw suppliers

Chemical Property of 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

Chemical Property:

Purity/Quality:

≥95% ^*data from raw suppliers

KetoZiprasidone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Keto Ziprasidone is an intermediate in the synthesis of Hydroxy Ziprasidone which is an impurity of Ziprasidone (Z485000); a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic.

Technology Process of 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

There total 2 articles about 5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 884305-06-0
6-chloro-5-(2-chloro-1-hydroxyethyl) indolin-2-one

: 87691-87-0
3-(1-piperazinyl)-1,2-benzisothiazole

: 118289-55-7
6-chloro-5-(2-chloroethyl)-2-oxindole

: 118307-04-3
6-chloro-5-(2-chloroacetyl) indolin-2-one

: 884305-08-2
5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-hydroxyethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

: 884305-07-1
5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

: 122883-93-6,199191-69-0,146939-27-7
ziprazidone

Guidance literature:: With tetrabutylammomium bromide; sodium carbonate; sodium iodide; In cyclohexane; Heating / reflux;

Reference yield:

: 87691-87-0
3-(1-piperazinyl)-1,2-benzisothiazole

: 118307-04-3
6-chloro-5-(2-chloroacetyl) indolin-2-one

: 884305-07-1
5-(2-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)-1-oxoethyl)-6-chloro-1,3-dihydro-2H-indole-2-one

Guidance literature:: With tetrabutylammomium bromide; sodium carbonate; sodium iodide; In cyclohexane; at 25 - 35 ℃; for 30 - 35h; Heating / reflux;