Technology Process of 7,4'-bis(benzoyloxy)-6-(3-hydroxy-3-methylbutyl)-5-tosyloxyisoflavone
There total 15 articles about 7,4'-bis(benzoyloxy)-6-(3-hydroxy-3-methylbutyl)-5-tosyloxyisoflavone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
acetone;
for 0.133333h;
microwave irradiation;
DOI:10.1016/j.tet.2006.06.066
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 82 percent / potassium carbonate / dimethylformamide / 1 h / 70 °C
2: potassium hydroxide / ethanol / 1 h / Heating
3: 5.48 g / aq. HCl / ethanol; CHCl3 / 1 h / 40 °C
4: 88 percent / potassium carbonate / dimethylformamide / 0.5 h / 60 - 70 °C
5: [hydroxy(tosyloxy)iodo]benzene / CHCl3 / 24 h / 20 °C
6: 3.82 g / aq. sodium hydroxide; methanol / CHCl3 / 5 h / 25 °C
7: 91 percent / triethylamine; PPh3; CuI / PdCl2 / dimethylformamide / 2 h / 80 °C
8: 88 percent / hydrogen / palladium on carbon / methanol; dioxane
9: 85 percent / potassium carbonate / acetone / 0.42 h / 45 °C
10: 84 percent / potassium carbonate / acetone / 2 h / Heating
With
hydrogenchloride; methanol; potassium hydroxide; sodium hydroxide; copper(l) iodide; [hydroxy(tosyloxy)iodo]benzene; hydrogen; potassium carbonate; triethylamine; triphenylphosphine;
palladium on activated charcoal; palladium dichloride;
In
1,4-dioxane; methanol; ethanol; chloroform; N,N-dimethyl-formamide; acetone;
DOI:10.1080/00397910500514121
- Guidance literature:
-
Multi-step reaction with 9 steps
1: potassium hydroxide / ethanol / 1 h / Heating
2: 5.48 g / aq. HCl / ethanol; CHCl3 / 1 h / 40 °C
3: 88 percent / potassium carbonate / dimethylformamide / 0.5 h / 60 - 70 °C
4: [hydroxy(tosyloxy)iodo]benzene / CHCl3 / 24 h / 20 °C
5: 3.82 g / aq. sodium hydroxide; methanol / CHCl3 / 5 h / 25 °C
6: 91 percent / triethylamine; PPh3; CuI / PdCl2 / dimethylformamide / 2 h / 80 °C
7: 88 percent / hydrogen / palladium on carbon / methanol; dioxane
8: 85 percent / potassium carbonate / acetone / 0.42 h / 45 °C
9: 84 percent / potassium carbonate / acetone / 2 h / Heating
With
hydrogenchloride; methanol; potassium hydroxide; sodium hydroxide; copper(l) iodide; [hydroxy(tosyloxy)iodo]benzene; hydrogen; potassium carbonate; triethylamine; triphenylphosphine;
palladium on activated charcoal; palladium dichloride;
In
1,4-dioxane; methanol; ethanol; chloroform; N,N-dimethyl-formamide; acetone;
DOI:10.1080/00397910500514121
