tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate

Base Information

• Chemical Name: tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate
• CAS No.: 1373558-72-5
• Molecular Formula: C₁₈H₂₆N₂O₇
• Molecular Weight: 382.414
• Mol file: 1373558-72-5.mol

Synonyms:tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate

Chemical Property of tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate

There total 1 articles about tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

6-(Boc-amino)-1-hexanol (75937-12-1) + 4-Nitrophenyl chloroformate (7693-46-1) → tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate (1373558-72-5)

Guidance literature:

With pyridine; In dichloromethane;

DOI:10.1039/c7ob02552a

Reference yield:

1H-pyrazolecarboxamidine hydrochloride (166197-22-4) + 3-(tert-butyloxycarbonylamino)propionic acid (3303-84-2) + tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate (1373558-72-5) + 1,5(S)-di-(tert-buyloxycarbonylamino)-6-(((4-nitrophenyloxy)carbonyl)oxy)hexane + Boc-Lys(Fmoc)-OH (84624-27-1) + acetic anhydride (108-24-7) → C133H249N43O34*8H(1+)

Guidance literature:

3-(tert-butyloxycarbonylamino)propionic acid; With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

With trifluoroacetic acid; In dichloromethane;

1H-pyrazolecarboxamidine hydrochloride; tert-butyl-(6-(((4-nitrophenoxy)carbonyl)oxy)hexyl)carbamate; 1,5(S)-di-(tert-buyloxycarbonylamino)-6-(((4-nitrophenyloxy)carbonyl)oxy)hexane; Boc-Lys(Fmoc)-OH; acetic anhydride; Further stages;

DOI:10.1039/c7ob02552a

upstream raw materials:

6-(Boc-amino)-1-hexanol

4-Nitrophenyl chloroformate