Carbamodithioic acid, dimethyl-, 4-pyridinyl ester (9CI)

Base Information

• Chemical Name: Carbamodithioic acid, dimethyl-, 4-pyridinyl ester (9CI)
• CAS No.: 89478-23-9
• Molecular Formula: C8H10 N2 S2
• Molecular Weight: 198.3084
• Mol file: 89478-23-9.mol

Synonyms:Carbamodithioic acid, dimethyl-, 4-pyridinyl ester (9CI)

Chemical Property of Carbamodithioic acid, dimethyl-, 4-pyridinyl ester (9CI)

Chemical Property:

• PSA: 73.52000
• LogP: 2.02020

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamodithioic acid, dimethyl-, 4-pyridinyl ester (9CI)

There total 3 articles about Carbamodithioic acid, dimethyl-, 4-pyridinyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-iodopyridine (15854-87-2) + Thiram (137-26-8,93196-73-7) → 4-pyridyl N,N-dimethyldithiocarbamate (89478-23-9)

Guidance literature:

With copper(I) oxide; caesium carbonate; In dimethyl sulfoxide; at 80 ℃; for 18h; Sealed tube;

DOI:10.1021/acs.orglett.7b02911

Reference yield: 25.0%

1N-(4-pyridyl)-2,4,6-triphenylpyridinium tetrafluoroborate + sodium dimethyldithiocarbamate (128-04-1) → 4-pyridyl N,N-dimethyldithiocarbamate (89478-23-9)

Guidance literature:

With 2,4,6-triphenylpyridine; at 235 - 240 ℃; for 3h; under 0.1 Torr;

DOI:10.1039/P19830002617

Reference yield:

4-aminopyridine (504-24-5) → 4-pyridyl N,N-dimethyldithiocarbamate (89478-23-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / ethanol / 2 h / Heating

2: 25 percent / 2,4,6-triphenylpyridine / 3 h / 235 - 240 °C / 0.1 Torr

With 2,4,6-triphenylpyridine; In ethanol;

DOI:10.1039/P19830002617

upstream raw materials:

sodium dimethyldithiocarbamate

4-aminopyridine

4-iodopyridine

Thiram

Refernces

• 1、 Katritzky Alan R.,Agha, Bushra J.,Awartani, Radi,Patel, Ranjan C.. "Nucleophilic Displacements of N-Aryl and Heteroaryl Groups. Part 4. Pyrylium-mediated Transformations of Heteroarylamines into Pyridinium Salts and their Inter- and Intra-molecular Displacement". . p. 2617 - 2621. Retrieved 2007/10/02.