2-Amino-3-ethoxypyrazine

Base Information

• Chemical Name: 2-Amino-3-ethoxypyrazine
• CAS No.: 89464-86-8
• Molecular Formula: C₆H₉N₃O
• Molecular Weight: 139.157
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID80540156
• Wikidata: Q72436599
• Mol file: 89464-86-8.mol

Synonyms:2-AMINO-3-ETHOXYPYRAZINE;89464-86-8;3-ethoxypyrazin-2-amine;MFCD08460065;Pyrazinamine, 3-ethoxy-;DTXSID80540156;AKOS006288504;CS-W021550;DS-10650;A861183;J-507788

Chemical Property of 2-Amino-3-ethoxypyrazine

Chemical Property:

• Vapor Pressure: 0.0176mmHg at 25°C
• Refractive Index: 1.553
• Boiling Point: 254.1 °C at 760 mmHg
• Flash Point: 107.4 °C
• PSA: 61.03000
• Density: 1.172g/cm³
• LogP: 1.03870
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 139.074561919
• Heavy Atom Count: 10
• Complexity: 99

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-3-ethoxypyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=NC=CN=C1N

Technology Process of 2-Amino-3-ethoxypyrazine

There total 1 articles about 2-Amino-3-ethoxypyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-amino-3-ethoxypyrazine (89464-86-8)

Guidance literature:

2-Amino-3-chlor-pyrazin, aethanol. Natriumaethylat, Siedetemp., 20 h;

Reference yield: 29.0%

α-bromoacetophenone (70-11-1) + 2-amino-3-ethoxypyrazine (89464-86-8) → 8-Ethoxy-2-phenyl-imidazo[1,2-a]pyrazine (183540-95-6)

Guidance literature:

In ethanol; for 6h; Heating;

DOI:10.1007/BF00807034

Reference yield: 22.0%

ethyl 2-bromo-3-oxo-3-phenylpropionate (55919-47-6) + 2-amino-3-ethoxypyrazine (89464-86-8) → ethyl 8-ethoxy-2-phenylimidazo<1,2-a>pyrazine-3-carboxylate

Guidance literature:

In ethanol; for 12h; Heating;

DOI:10.1016/0223-5234(93)90150-D

Downstream raw materials:

8-Ethoxy-2-phenyl-imidazo[1,2-a]pyrazine

(8-Ethoxy-2-phenyl-imidazo[1,2-a]pyrazin-3-yl)-acetonitrile

(8-Ethoxy-2-phenyl-imidazo[1,2-a]pyrazin-3-ylmethyl)-dimethyl-amine