Technology Process of PYRAN-3-CARBONITRILE, TETRAHYDRO-
There total 4 articles about PYRAN-3-CARBONITRILE, TETRAHYDRO- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium tert-butylate;
In
1,2-dimethoxyethane; tert-butyl alcohol;
at 0 - 20 ℃;
for 3.5h;
DOI:10.3987/COM-10-S(E)73
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridinium chlorochromate / dichloromethane / 2.5 h / 20 °C / Molecular sieve
2: potassium tert-butylate / 1,2-dimethoxyethane; tert-butyl alcohol / 3.5 h / 0 - 20 °C
With
potassium tert-butylate; pyridinium chlorochromate;
In
1,2-dimethoxyethane; dichloromethane; tert-butyl alcohol;
DOI:10.3987/COM-10-S(E)73
- Guidance literature:
-
Multi-step reaction with 4 steps
1: borane-THF / tetrahydrofuran / 3 h / 0 °C
2: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 0 - 20 °C
3: pyridinium chlorochromate / dichloromethane / 2.5 h / 20 °C / Molecular sieve
4: potassium tert-butylate / 1,2-dimethoxyethane; tert-butyl alcohol / 3.5 h / 0 - 20 °C
With
borane-THF; potassium tert-butylate; dihydrogen peroxide; pyridinium chlorochromate; sodium hydroxide;
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; water; tert-butyl alcohol;
DOI:10.3987/COM-10-S(E)73
