4-(p-methoxyphenyl)-3,5-dihydroxypyrazole

Base Information

• Chemical Name: 4-(p-methoxyphenyl)-3,5-dihydroxypyrazole
• CAS No.: 106367-56-0
• Molecular Formula: C₉H₇ClN₂O₂
• Molecular Weight: 210.62
• Mol file: 106367-56-0.mol

Synonyms:4-(p-methoxyphenyl)-3,5-dihydroxypyrazole

Chemical Property of 4-(p-methoxyphenyl)-3,5-dihydroxypyrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(p-methoxyphenyl)-3,5-dihydroxypyrazole

There total 2 articles about 4-(p-methoxyphenyl)-3,5-dihydroxypyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

diethyl 2-(p-chlorophenyl)malonate (19677-37-3) → 4-(p-methoxyphenyl)-3,5-dihydroxypyrazole (106367-56-0)

Guidance literature:

With hydrazine hydrate; for 2h; Heating;

DOI:10.1021/jo00341a023

Reference yield:

C12H7ClN2O2 (79815-62-6) → Malondialdehyde (542-78-9) + 4-(p-methoxyphenyl)-3,5-dihydroxypyrazole (106367-56-0)

Guidance literature:

With morpholine; In water; acetonitrile; at 25 ℃; Rate constant; other solvents;

DOI:10.1021/jo00341a023

Reference yield: 40.0%

4-(p-methoxyphenyl)-3,5-dihydroxypyrazole (106367-56-0) + acetylacetone (123-54-6,81235-32-7) → 5.7-Dimethyl-2-(p-chlorphenyl)-1-oxo-1H-pyrazol<1.2-a>pyrazol-4-ium-3-olat (76426-56-7)

Guidance literature:

for 0.0833333h; Heating;

DOI:10.1021/jo00341a023

upstream raw materials:

diethyl 2-(p-chlorophenyl)malonate

C₁₂H₇ClN₂O₂

Downstream raw materials:

C₁₂H₇ClN₂O₂

7-Amino-2-(4-chloro-phenyl)-3-hydroxy-5-imino-6-phenyl-5H-pyrazolo[1,2-a]pyrazol-1-one

7-Amino-2-(4-chloro-phenyl)-3-hydroxy-5-imino-6-(4-methoxy-phenyl)-5H-pyrazolo[1,2-a]pyrazol-1-one

5.7-Dimethyl-2-(p-chlorphenyl)-1-oxo-1H-pyrazol<1.2-a>pyrazol-4-ium-3-olat