(2-TERT-BUTOXYCARBONYLAMINO-THIAZOL-4-YL)-ACETIC ACID

Base Information

Chemical Name:(2-TERT-BUTOXYCARBONYLAMINO-THIAZOL-4-YL)-ACETIC ACID
CAS No.:89336-46-9
Molecular Formula:C10H14N2O4S
Molecular Weight:258.298
Hs Code.:2934100090
Mol file:89336-46-9.mol

Synonyms:{2-[(Tert-butoxycarbonyl)amino]-1,3-thiazol-4-yl}acetic acid;Boc-2-amino-4-thiazole acetic acid;

Suppliers and Price of (2-TERT-BUTOXYCARBONYLAMINO-THIAZOL-4-YL)-ACETIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-BOC-2-AMINO-4-THIAZOLACETIC ACID 95.00%
1G
$ 866.13

Biosynth Carbosynth
Boc-2-amino-4-thiazole acetic acid
2 g
$ 1012.50

Biosynth Carbosynth
Boc-2-amino-4-thiazole acetic acid
5 g
$ 1620.00

Biosynth Carbosynth
Boc-2-amino-4-thiazole acetic acid
1 g
$ 632.90

Biosynth Carbosynth
Boc-2-amino-4-thiazole acetic acid
500 mg
$ 395.00

Biosynth Carbosynth
Boc-2-amino-4-thiazole acetic acid
250 mg
$ 247.50

Chemenu
N-BOC-2-amino-4-thiazolaceticacid 97%
10g
$ 271.00

Chemenu
N-BOC-2-amino-4-thiazolaceticacid 97%
25g
$ 542.00

Chem-Impex
2-[2-[(tert-Butoxycarbonyl)amino]thiazol-4-yl]aceticacid,≥98%(HPLC) ≥98%(HPLC)
250MG
$ 50.85

Crysdot
2-[2-[(tert-Butoxycarbonyl)amino]thiazol-4-yl]acetic Acid 97%
1g
$ 60.00

Total 31 raw suppliers

Chemical Property of (2-TERT-BUTOXYCARBONYLAMINO-THIAZOL-4-YL)-ACETIC ACID

Chemical Property:

Melting Point:168 °C
PKA:5.20±0.70(Predicted)
PSA：116.76000
Density:1.37 g/cm³
LogP:2.19020
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

N-BOC-2-AMINO-4-THIAZOLACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Boc-2-amino-4-thiazole Acetic Acid is a reactant that is used in the preparation of phenylhydroxylmethylpyrrolidinylmetylphenylthiozolylacetaimde deriivatives as human β3 adrenergic receptor agonists via multi step synthesis.

Technology Process of (2-TERT-BUTOXYCARBONYLAMINO-THIAZOL-4-YL)-ACETIC ACID

There total 9 articles about (2-TERT-BUTOXYCARBONYLAMINO-THIAZOL-4-YL)-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 82548-78-5
ethyl {2-[(tert-butoxycarbonyl)amino]-1,3-thiazol-4-yl}acetate

: 89336-46-9
2-{2[(tert-butoxycarbonyl)amino]-1,3-thiazol-4-yl}acetic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; methanol; water; at 20 ℃; for 5h;
DOI:10.1021/acsmedchemlett.8b00506

Reference yield: 92.0%

: 29676-71-9
2-amino-4-thiazoleacetic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 89336-46-9
2-{2[(tert-butoxycarbonyl)amino]-1,3-thiazol-4-yl}acetic acid

Guidance literature:: In isopropyl alcohol; at 0 - 20 ℃; for 12h; Solvent;

Reference yield: 81.6%

: 53266-94-7
ethyl 2-amino-1,3-thiazol-4-acetate

: 24424-99-5
di-tert-butyl dicarbonate

: 89336-46-9
2-{2[(tert-butoxycarbonyl)amino]-1,3-thiazol-4-yl}acetic acid

Guidance literature:: ethyl 2-amino-1,3-thiazol-4-acetate; di-tert-butyl dicarbonate; With dmap; In dichloromethane; at 30 ℃;

With lithium hydroxide monohydrate; water; In ethanol; at 40 ℃; for 2h; Temperature;