methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate

Base Information

• Chemical Name: methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate
• CAS No.: 116047-34-8
• Molecular Formula: C₃₀H₂₂Br₂O₂
• Molecular Weight: 574.311
• Mol file: 116047-34-8.mol

Synonyms:methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate

Chemical Property of methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate

There total 5 articles about methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

trimethyl phosphonoacetate (5927-18-4) + 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzxanthylium tetrafluoroborate → methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate (116047-34-8)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 2h; Ambient temperature; Heating;

DOI:10.1016/0040-4039(88)85314-0

Reference yield:

7-bromo-3,4-dihydro-2H-naphthalen-1-one (32281-97-3) → methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate (116047-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 percent / BF₃OEt₂

2: 45 percent / sodium hydride / tetrahydrofuran / 2 h / Ambient temperature; Heating

With boron trifluoride diethyl etherate; sodium hydride; In tetrahydrofuran;

DOI:10.1016/0040-4039(88)85314-0

Reference yield:

7-bromo-2-benzylidene-1-tetralone (116047-27-9) → methyl 2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrobenzanthracene-14-carboxylate (116047-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: BF₃*Et₂O / 5 h / 100 °C

2: sodium hydride / tetrahydrofuran / 5 h / Ambient temperature

With boron trifluoride diethyl etherate; sodium hydride; In tetrahydrofuran;

DOI:10.1021/ja00001a027

upstream raw materials:

trimethyl phosphonoacetate

methyl(dimethylphosphinyl)acetate

7-bromo-3,4-dihydro-2H-naphthalen-1-one

7-benzylidene-2-bromo-α-tetralone

Downstream raw materials:

methyl 2,12-bis(2,7-dimethoxyacridin-9-yl)-7-phenyl-5,6,8,9-tetrahydrodibenzanthracene-14-carboxylate

methyl 2,12-dibromo-7-phenylbenzanthracene-14-carboxylate

2,12-dibromo-7-phenyl-5,6,8,9-tetrahydrodibenzanthracene-14-carboxylic acid

methyl 2,12-diiodo-7-phenyl-5,6,8,9-tetrahydrodibenzanthracene-14-carboxylate