Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

Base Information

Chemical Name:Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate
CAS No.:89228-42-2
Molecular Formula:C12H14 O3
Molecular Weight:206.241
Hs Code.:
DSSTox Substance ID:DTXSID90526608
Wikidata:Q82395223
Mol file:89228-42-2.mol

Synonyms:89228-42-2;methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate;2-NAPHTHALENECARBOXYLIC ACID, 5,6,7,8-TETRAHYDRO-4-HYDROXY-METHYL ESTER;4-hydroxy-5,6,7,8-tetrahydro-naphthalene-2-carboxylic acid methyl ester;SCHEMBL19579743;DTXSID90526608;MFCD07779371;2-Naphthalenecarboxylic acid,5,6,7,8-tetrahydro-4-hydroxy-methyl ester;AKOS022648640;CS-W000576;AS-39912;methyl4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

Suppliers and Price of Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate 97%
1g
$ 451.00

Chemenu
Methyl4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate 95+%
1g
$ 425.00

American Custom Chemicals Corporation
METHYL-5,6,7,8-TETRAHYDRO-4-HYDROXY-2-NAPHTHALENECARBOXYLATE 98.00%
5MG
$ 500.28

Alichem
2-Naphthalenecarboxylicacid,5,6,7,8-tetrahydro-4-hydroxy-methylester
1g
$ 1685.00

Alichem
2-Naphthalenecarboxylicacid,5,6,7,8-tetrahydro-4-hydroxy-methylester
500mg
$ 980.00

Total 8 raw suppliers

Chemical Property of Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

Chemical Property:

PSA：46.53000
LogP:2.05760
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:206.094294304
Heavy Atom Count:15
Complexity:239

Purity/Quality:

98%min ^*data from raw suppliers

Methyl4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC2=C(CCCC2)C(=C1)O

Technology Process of Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

There total 4 articles about Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.2%

: 34205-71-5
methyl 4-hydroxy-2-naphthalenecarboxylate

: 89228-42-2
Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

Guidance literature:: With hydrogen; palladium(II) hydroxide; In methanol; at 20 ℃; for 16h; under 19001.3 Torr;

Reference yield: 83.0%

: 872-36-6
vinylene carbonate

: 85531-80-2
methyl 2-oxo-2,5,6,7,8-pentahydro-2H-benzo[b]pyran-3-ylcarboxylate

: 89228-42-2
Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

Guidance literature:: In 1,3,5-trimethyl-benzene; at 180 ℃; for 40h;
DOI:10.1016/S0040-4039(01)99816-8 DOI:10.1021/jo00195a033

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 89228-42-2
Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / lithium diisopropylamide / tetrahydrofuran / 2.75 h / -30 - 25 °C

2: 83 percent / 1,3,5-trimethyl-benzene / 40 h / 180 °C

With lithium diisopropyl amide; In tetrahydrofuran; 1,3,5-trimethyl-benzene;
DOI:10.1021/jo00195a033