34205-71-5

Usage

Uses

Used in Pharmaceutical Industry:
2-Naphthalenecarboxylic acid, 4-hydroxy-, Methyl ester is used as an intermediate in the production of pharmaceuticals for its potential biological activity.
Used in Organic Synthesis:
2-Naphthalenecarboxylic acid, 4-hydroxy-, Methyl ester serves as a precursor in the synthesis of various organic compounds, contributing to the development of new chemical entities.
Used in Fragrance Industry:
2-Naphthalenecarboxylic acid, 4-hydroxy-, Methyl ester is utilized as a precursor in the production of fragrances, adding to the complexity and variety of scents in the market.
Used in Specialty Chemicals Production:
It is also employed in the creation of specialty chemicals, where its unique properties can be harnessed for specific applications.
Used in Antioxidant and Anti-Inflammatory Research:
2-Naphthalenecarboxylic acid, 4-hydroxy-, Methyl ester has been studied for its potential antioxidant and anti-inflammatory properties, indicating possible uses in the development of treatments for related conditions.

InChI:InChI=1/C12H10O3/c1-15-12(14)9-6-8-4-2-3-5-10(8)11(13)7-9/h2-7,13H,1H3

Upstream product

• 100-52-7 benzaldehyde 
• 106-65-0 Dimethyl succinate 
• 573-57-9 1,4-epoxy-1,4-dihydronaphthalene 
• 67-56-1 methanol 
• 127265-98-9 methyl 4-acetoxy-2-naphthoate 
• 1573-91-7 3-hydroxynaphthoic acid 

Downstream Products

• 128300-09-4 (+)-(1S)-5-(benzyloxy)-3-(tert-butyloxycarbonyl)-1-(hydroxymethyl)-1,2-dihydro-3H-benzindole 
• 128300-11-8 5-(benzyloxy)-3-(tert-butyloxycarbonyl)-1-(chloromethyl)-1,2-dihydro-3H-benzindole 
• 122745-36-2 N-(tert-butyloxycarbonyl)-4-(benzyloxy)-2-naphthylamine 
• 161646-53-3 tert-butyl (4-(benzyloxy)-1-iodonaphthalen-2-yl)carbamate 
• 1116653-76-9 (R)-tert-butyl (4-(benzyloxy)-1-iodonaphthalen-2-yl)(oxiran-2-ylmethyl)carbamate 
• 33295-47-5 methyl 4-methoxynaphthalene-2-carboxylate 
• 89228-42-2 Methyl 4-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carboxylate 

Relevant academic research and scientific papers

Preparations of SF5- and CF3-substituted arenes utilizing the 7-oxabicyclo[2.2.1]hept-2-ene synthones

The synthesis of SF5- and CF3-substituted benzenes and naphthalenes from various 7-oxanorbornene derivatives utilizing SF 5Cl and CF3I radical addition reactions, followed by dehydrohalogenation and aromatizatio

BENZOINDAZOLONE COMPOUND, AND INTERMEDIATE THEREOF

The present invention relates to a benzoindazolone compound, or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, diasteromer, tautomer or prodrug thereof; and an intermediate thereof. A compound according to the present invention is used as a substrate for NQO1 to facilitate a redox reaction of NQO1, and thus is expected to be developable as a medicine for preventing or treating inflammatory diseases.

CYTOTOXIC AGENTS

The present invention provides a compound of formula (I): (T-X4)p-B1-X3-A-X2-L-X1-AM or pharmaceutically acceptable salts, tautomers, stereoisomers or mixtures thereof; wherein AM is (AM1); (AM2); or (AM3); with the proviso that the compound of formula (I) contains at least one sigma hole group; and with the proviso that no more than one of A, B1 and T is a sigma hole group; and each sigma hole group is independently: (SH1); (SH2); (SH3); (SH4); (SH5); (SH6); (SH7); (SH8); (SH9); or (SH10).

Rhodium-Catalyzed Twofold Unsymmetrical C-H Alkenylation-Annulation/Thiolation Reaction to Access Thiobenzofurans

A Rh(III)-catalyzed twofold unsymmetrical C-H alkenylation-annulation/thiolation reaction has been developed, enabling the straightforward and efficient synthesis of various thiobenzofurans in one step. This robust protocol proceeds with a broad substrate scope and good functional group tolerance under relatively mild reaction conditions.

G-A CROSSLINKING CYTOTOXIC AGENTS

The invention relates to a compound of formula (I): or salts, solvates, isomers or tautomers thereof, wherein; A is a group selected from: R1 is selected from H and halogen; either R2 is selected from -CH2-halogen, C1

Organic dye-catalyzed radical ring expansion reaction

Herein, we reported an attractive method for synthesizing medium-sized rings that are catalyzed by erythrosine B under fluorescent light irradiation. This synthetic approach featured mild conditions, a facile procedure, a broad substrate scope, and modera

Ring Opening of Bicyclo[3.1.0]hexan-2-ones: A Versatile Synthetic Platform for the Construction of Substituted Benzoates

Described is the development of a highly efficient 2πdisrotatory ring-opening aromatization sequence using bicyclo[3.1.0]hexan-2-ones. This unprecedented transformation efficiently proceeds under thermal conditions and allows facile construction of uniquely substituted and polyfunctionalized benzoates. In the presence of either amines or alcohols formation of substituted anilines or ethers, respectively, is achieved. Additionally, the utility of this method was demonstrated in a short synthesis of sekikaic acid methyl ester. Cracked open: A highly efficient thermal 2πdisrotatory ring-opening aromatization sequence of bicyclo[3.1.0]hexan-2-ones is described. The transformation proceeds in sulfolane to give uniquely substituted benzoates. In the presence of either amines or alcohols, formation of substituted anilines or ethers, respectively, is achieved.

NOVEL COMPOUNDS AND THEIR USE IN THERAPY

The invention provides compounds which inhibit N-myristoyltransferase and are selective for protozoal N-myristoyltransferase and, consequently suitable to treat microbial infections, including viral and fungal infections, and protozoan infections such as malaria, leishmaniasis and sleeping sickness.