dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate

Base Information

• Chemical Name: dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate
• CAS No.: 247170-98-5
• Molecular Formula: C₂₇H₃₈N₄O₆
• Molecular Weight: 514.622
• Mol file: 247170-98-5.mol

Synonyms:dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate

Chemical Property of dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate

There total 3 articles about dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

dibenzyl {[(2-aminoethyl)azanediyl]bis(ethane-2,1-diyl)}dicarbamate (247170-99-6) + di-tert-butyl dicarbonate (24424-99-5) → dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate (247170-98-5)

Guidance literature:

With sodium hydrogencarbonate; sodium chloride; In dichloromethane; water; at 20 ℃;

DOI:10.1021/ja503456r

Reference yield: 41.0%

benzyl chloroformate (501-53-1,94274-21-2) + N,N-bis(2-aminoethyl)-N-[2-(N-t-butoxycarbonylamino)ethyl]amine (179167-09-0) → dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate (247170-98-5)

Guidance literature:

With potassium carbonate; In 1,4-dioxane; water; for 1h; pH=7 - 8;

Reference yield:

2,2',2''-triaminotriethylamine (4097-89-6) + N-(benzyloxycarbonyl)aniline (3422-02-4) → dibenzyl tert-butyl(nitrilotris(ethane-2,1-diyl))tricarbamate (247170-98-5)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 12 h / 20 °C / Inert atmosphere; Cooling with ice

2: sodium chloride; sodium hydrogencarbonate / water; dichloromethane / 20 °C

With sodium hydrogencarbonate; sodium chloride; In dichloromethane; water;

upstream raw materials:

benzyl chloroformate

N,N-bis(2-aminoethyl)-N-[2-(N-t-butoxycarbonylamino)ethyl]amine

dibenzyl {[(2-aminoethyl)azanediyl]bis(ethane-2,1-diyl)}dicarbamate

di-tert-butyl dicarbonate

Downstream raw materials:

dibenzyl {[(2-aminoethyl)azanediyl]bis(ethane-2,1-diyl)}dicarbamate