4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

Base Information

Chemical Name:4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol
CAS No.:1062671-19-5
Molecular Formula:C₂₁H₂₆N₄O₂
Molecular Weight:366.463
Hs Code.:

Synonyms:4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

Suppliers and Price of 4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

There total 14 articles about 4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1062671-23-1
{4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-6-methylpyridin-2-yl}diethylamine

: 1062671-19-5
4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; ethanol; at 20 ℃; for 5h; under 750.075 Torr; Inert atmosphere;
DOI:10.1021/jm4014696

Reference yield:

: 1010113-45-7
4-benzyloxy-3-ethyl-5-methylbenzoic acid hydrazide

: 1062671-19-5
4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane; N,N-dimethyl-formamide / 1.17 h / 20 °C / Inert atmosphere

2: Burgess Reagent / tetrahydrofuran / 0.08 h / 110 °C / Microwave irradiation; Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; ethanol / 5 h / 20 °C / 750.08 Torr / Inert atmosphere

With Burgess Reagent; palladium 10% on activated carbon; hydrogen; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm4014696

Reference yield:

: 1062671-21-9
4-benzyloxy-3-ethyl-5-methyl-benzoic acid N'-(2-diethylamino-6-methyl-pyridine-4-carbonyl)-hydrazide

: 1062671-19-5
4-(5-(2-(diethylamino)-6-methylpyridin-4-yl)-1,3,4-oxadiazol-2-yl)-2-ethyl-6-methylphenol

Guidance literature:: Multi-step reaction with 2 steps

1: Burgess Reagent / tetrahydrofuran / 0.08 h / 110 °C / Microwave irradiation

2: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; ethanol / 5 h / 20 °C / 750.08 Torr

With Burgess Reagent; hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; ethanol;