C₃₃H₃₅O₂P

Base Information

• Chemical Name: C₃₃H₃₅O₂P
• CAS No.: 1312606-29-3
• Molecular Formula: C₃₃H₃₅O₂P
• Molecular Weight: 494.613
• Mol file: 1312606-29-3.mol

Synonyms:C₃₃H₃₅O₂P

Chemical Property of C₃₃H₃₅O₂P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₃₅O₂P

There total 5 articles about C₃₃H₃₅O₂P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H17ClO + 2-(di-p-tolylphosphino)phenol (1312606-26-0) → C33H35O2P (1312606-29-3)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/ol2013236

Reference yield:

2-(tetrahydropyran-2-yloxy)phenyl bromide (57999-46-9) → C33H35O2P (1312606-29-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane / dimethyl sulfoxide / 12 h / 20 - 100 °C

2.1: toluene-4-sulfonic acid / methanol / 20 °C

3.1: trichlorosilane; N,N-dimethyl-aniline / toluene / 16 h / 20 - 80 °C

3.2: 0.5 h / 0 - 50 °C

4.1: triethylamine / dichloromethane / 0 - 20 °C

With trichlorosilane; palladium diacetate; toluene-4-sulfonic acid; N,N-dimethyl-aniline; triethylamine; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In methanol; dichloromethane; dimethyl sulfoxide; toluene;

DOI:10.1021/ol2013236

Reference yield:

(1R,4R,7R)-7-isopropyl-5-methylbicyclo[2.2.2]octane-2,5-diene-2-carboxylic acid (1252606-18-0) → C33H35O2P (1312606-29-3)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl dichloride / dichloromethane / 12 h / 20 °C

2: triethylamine / dichloromethane / 0 - 20 °C

With oxalyl dichloride; triethylamine; In dichloromethane;

DOI:10.1021/ol2013236

upstream raw materials:

(1R,4R,7R)-7-isopropyl-5-methylbicyclo[2.2.2]octane-2,5-diene-2-carboxylic acid

2-(di-p-tolylphosphino)phenol

C₂₅H₂₇O₃P

2-(tetrahydropyran-2-yloxy)phenyl bromide