2-(5-Fluoro-1H-indazol-3-YL)acetic acid

Base Information

Chemical Name:2-(5-Fluoro-1H-indazol-3-YL)acetic acid
CAS No.:885271-22-7
Molecular Formula:C₉H₇FN₂O₂
Molecular Weight:194.165
Hs Code.:
DSSTox Substance ID:DTXSID10696473
Wikidata:Q82626070
Mol file:885271-22-7.mol

Synonyms:885271-22-7;2-(5-FLUORO-1H-INDAZOL-3-YL)ACETIC ACID;(5-FLUORO-1H-INDAZOL-3-YL)-ACETIC ACID;(5-FLUORO-1H-INDAZOL-3-YL)ACETIC ACID;2-(5-fluoro-2H-indazol-3-yl)acetic acid;SCHEMBL14979246;DTXSID10696473;MILWWVRZISGHQU-UHFFFAOYSA-N;BCP29634;MFCD06739143;AKOS006228326;AB28697;AS-64146;CS-0102739;FT-0736089;(5-FLUORO-2H-INDAZOL-3-YL)ACETIC ACID;D76304;2-(5-FLUORO-1H-INDAZOL-3-YL)ACETICACID;A862127;(5-Fluoro-1H-indazol-3-yl)-acetic acid, AldrichCPR;5-Fluoro-1H-indazole-3-acetic acid pound>>1H-Indazole-3-aceticacid,5-fluoro-

Suppliers and Price of 2-(5-Fluoro-1H-indazol-3-YL)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(5-Fluoro-1H-indazol-3-yl)-aceticAcid
100mg
$ 285.00

SynQuest Laboratories
2-(5-Fluoro-1H-indazol-3-yl)acetic acid 96%
250 mg
$ 643.00

SynQuest Laboratories
2-(5-Fluoro-1H-indazol-3-yl)acetic acid 96%
1 g
$ 1734.00

J&W Pharmlab
(5-Fluoro-1H-indazol-3-yl)-aceticacid 98%
5g
$ 1998.00

J&W Pharmlab
(5-Fluoro-1H-indazol-3-yl)-aceticacid 98%
1g
$ 598.00

Crysdot
2-(5-Fluoro-1H-indazol-3-yl)aceticacid 97%
1g
$ 586.00

Crysdot
2-(5-Fluoro-1H-indazol-3-yl)aceticacid 97%
250mg
$ 245.00

Chemenu
(5-Fluoro-1H-indazol-3-yl)-aceticacid 97%
1g
$ 830.00

Anichem
(5-Fluoro-1H-indazol-3-yl)-aceticacid >95%
5g
$ 2650.00

Anichem
(5-Fluoro-1H-indazol-3-yl)-aceticacid >95%
1g
$ 780.00

Total 17 raw suppliers

Chemical Property of 2-(5-Fluoro-1H-indazol-3-YL)acetic acid

Chemical Property:

Vapor Pressure:2.1E-08mmHg at 25°C
Refractive Index:1.676
Boiling Point:436.9°C at 760 mmHg
PKA:3.85±0.30(Predicted)
Flash Point:218°C
PSA：65.98000
Density:1.531g/cm³
LogP:1.32910
Storage Temp.:2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:194.04915563
Heavy Atom Count:14
Complexity:237

Purity/Quality:

97% ^*data from raw suppliers

(5-Fluoro-1H-indazol-3-yl)-aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NNC(=C2C=C1F)CC(=O)O

Technology Process of 2-(5-Fluoro-1H-indazol-3-YL)acetic acid

There total 2 articles about 2-(5-Fluoro-1H-indazol-3-YL)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.6%

: 3-amino-3-(5-fluoro-2-nitrophenyl)propionic acid

: 885271-22-7
2-(5-fluoro-1H-indazol-3-yl)acetic acid

Guidance literature:: With hydrazine hydrate; sodium hydroxide; at 80 ℃; for 0.5h;

Reference yield:

: 395-81-3
5-fluoro-2-nitrobenzaldehyde

: 885271-22-7
2-(5-fluoro-1H-indazol-3-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: formic acid / 0.5 h / 45 °C

1.2: 5 h / 45 - 95 °C

2.1: hydrazine hydrate; sodium hydroxide / 0.5 h / 80 °C

With formic acid; hydrazine hydrate; sodium hydroxide;