4-BOC-AMINO-1-[1-(4-FLUORO-BENZYL)-1H-BENZOIMIDAZOL-2-YL]-PIPERIDINE

Base Information

• Chemical Name: 4-BOC-AMINO-1-[1-(4-FLUORO-BENZYL)-1H-BENZOIMIDAZOL-2-YL]-PIPERIDINE
• CAS No.: 885270-85-9
• Molecular Formula: C₂₄H₂₉FN₄O₂
• Molecular Weight: 424.518
• Hs Code.: 2933990090
• Mol file: 885270-85-9.mol

Synonyms:4-BOC-AMINO-1-[1-(4-FLUORO-BENZYL)-1H-BENZOIMIDAZOL-2-YL]-PIPERIDINE

Chemical Property of 4-BOC-AMINO-1-[1-(4-FLUORO-BENZYL)-1H-BENZOIMIDAZOL-2-YL]-PIPERIDINE

Chemical Property:

• PSA: 59.39000
• LogP: 5.17310

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl N-(1-{1-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}piperidin-4-yl)carbamate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BOC-AMINO-1-[1-(4-FLUORO-BENZYL)-1H-BENZOIMIDAZOL-2-YL]-PIPERIDINE

There total 1 articles about 4-BOC-AMINO-1-[1-(4-FLUORO-BENZYL)-1H-BENZOIMIDAZOL-2-YL]-PIPERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(piperidin-4-yl)carbamic acid tert-butyl ester (73874-95-0) + 2-chloro-1-(4-fluorobenzyl)-1H-benzimidazole (84946-20-3) → C24H29FN4O2 (885270-85-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; at 120 ℃; Neat (no solvent);

DOI:10.1016/j.bmcl.2009.05.086

Reference yield:

C24H29FN4O2 (885270-85-9) + methyl iodide (74-88-4) → C25H31FN4O2

Guidance literature:

With sodium hydride;

DOI:10.1016/j.bmcl.2009.05.086

upstream raw materials:

(piperidin-4-yl)carbamic acid tert-butyl ester

2-chloro-1-(4-fluorobenzyl)-1H-benzimidazole

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