2-(4-methoxyphenyl)amino-2-phenylethanol

Base Information

• Chemical Name: 2-(4-methoxyphenyl)amino-2-phenylethanol
• CAS No.: 135286-00-9
• Molecular Formula: C₁₅H₁₇NO₂
• Molecular Weight: 243.305
• Mol file: 135286-00-9.mol

Synonyms:2-(4-methoxyphenyl)amino-2-phenylethanol

Chemical Property of 2-(4-methoxyphenyl)amino-2-phenylethanol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(4-methoxyphenyl)amino-2-phenylethanol

There total 15 articles about 2-(4-methoxyphenyl)amino-2-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(2-benzoyloxy-1-phenylethyl)-4-methoxyphenylamide (1049016-46-7) → 2-(4-methoxyphenyl)amino-2-phenylethanol (135286-00-9)

Guidance literature:

With potassium hydroxide; In methanol; water; at 20 ℃; for 5h;

DOI:10.1021/ol8014978

Reference yield: 99.0%

styrene oxide (96-09-3) + 4-methoxy-aniline (104-94-9) → 2-(4-methoxyphenyl)amino-2-phenylethanol (135286-00-9)

Guidance literature:

With {Co³⁺-Cd²⁺} metal-organic framework; at 20 ℃; for 4h; neat (no solvent);

DOI:10.1039/c1dt10602c

Reference yield: 93.0%

(4-methoxy-phenylimino)-phenyl-acetic acid methyl ester (51335-08-1) → 2-(4-methoxyphenyl)amino-2-phenylethanol (135286-00-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 70 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.1c03662

upstream raw materials:

styrene oxide

4-methoxy-aniline

methanol

benzaldehyde

Downstream raw materials:

(2R,4S)-2-methyl-3-(p-methoxyphenyl)-2,4-diphenyl-1,3,2-oxazosilolidine