2-(Methylamino)benzeneethanol

Base Information

• Chemical Name: 2-(Methylamino)benzeneethanol
• CAS No.: 106899-00-7
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.208
• European Community (EC) Number: 851-643-6
• Nikkaji Number: J1.190.525K
• Mol file: 106899-00-7.mol

Synonyms:2-(Methylamino)benzeneethanol;106899-00-7;2-[2-(methylamino)phenyl]ethanol;SCHEMBL932125;2-[2-(methylamino)phenyl]ethan-1-ol;AKOS015960609;EN300-6505012

Chemical Property of 2-(Methylamino)benzeneethanol

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 151.099714038
• Heavy Atom Count: 11
• Complexity: 106

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CNC1=CC=CC=C1CCO

Technology Process of 2-(Methylamino)benzeneethanol

There total 10 articles about 2-(Methylamino)benzeneethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-ethyl ethyl carbonate → 2-ethanol (106899-00-7)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 1h; Heating;

Reference yield: 95.0%

1-(methoxymethyl)indolin-2-one (240798-84-9) → 2-ethanol (106899-00-7)

Guidance literature:

With sodium tetrahydroborate; In ethanol; Ambient temperature;

DOI:10.1021/jo990549k

Reference yield: 93.0%

N-(2-methoxyethoxymethyl)oxindole → 2-ethanol (106899-00-7)

Guidance literature:

With sodium tetrahydroborate; In ethanol; Ambient temperature;

DOI:10.1021/jo990549k

upstream raw materials:

2-aminophenethyl alcohol

methyl iodide

1-(methoxymethyl)indolin-2-one

N-formyl-2-aminophenethyl alcohol

Downstream raw materials:

(E)-3-{[2-(2-Hydroxy-ethyl)-phenyl]-methyl-carbamoyl}-acrylic acid ethyl ester

N-[2-(2-hydroxyethyl)phenyl]-N-methylcarbamic acid tert-butyl ester

N-(o-Ethenylphenyl)-N-methyl-2,2-bis(phenylthio)acetamide

2,2-Dichloro-N-(o-ethenylphenyl)-N-methylacetamide

Refernces

• 1、 Mitsunaga, Shintaro,Ohbayashi, Tohru,Sugiyama, Shimpei,Saitou, Takahito,Tadokoro, Makoto,Satoh, Tsuyoshi. "Asymmetric synthesis of cyclic α-amino acid derivatives by the intramolecular reaction of magnesium carbenoid with an N-magnesio arylamine". experimental part. p. 1697 - 1708. Retrieved 2009/12/06.
• 2、 Wang, Jeh-Jeng,Hu, Wan-Ping. "Novel 3-Aza-Grob Fragmentation in Hydride Reduction of Ether-Protected Aromatic Lactams". . p. 5725 - 5727. Retrieved 2007/10/03.