5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate

Base Information

• Chemical Name: 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate
• CAS No.: 1210430-94-6
• Molecular Formula: C₈H₈O₃*C₁₀H₁₆N₂O₃S
• Molecular Weight: 396.464
• Mol file: 1210430-94-6.mol

Synonyms:5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate

Chemical Property of 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate

There total 2 articles about 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-Mandelic Acid (611-71-2) + 5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide (112101-81-2) → 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate (1210430-94-6)

Guidance literature:

In methanol; water; at 65 ℃; for 6h;

Reference yield:

(+/-)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide (112244-38-9) + (R)-Mandelic Acid (611-71-2) → C8H8O3*C10H16N2O3S + 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate (1210430-94-6)

Guidance literature:

In methanol; optical yield given as %ee; Resolution of racemate;

DOI:10.1016/j.ejmech.2010.09.042

Reference yield:

5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide D-mandelate (1210430-94-6) → 5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide (112101-81-2)

Guidance literature:

With potassium carbonate; In water; at 20 ℃; for 3h;

DOI:10.1016/j.ejmech.2010.09.042

upstream raw materials:

(+/-)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide

(R)-Mandelic Acid

5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide

Downstream raw materials:

5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide

2-methoxy-5-[(2R)-2-(piperazin-1-yl)propyl]benzenesulfonamide

2-methoxy-5-[(2R)-2-(4-methylpiperazin-1-yl)propyl]benzenesulfonamide

2-methoxy-5-[(2R)-2-(4-ethylpiperazin-1-yl)propyl]benzenesulfonamide