N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

Base Information

Chemical Name:N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide
CAS No.:1082828-00-9
Molecular Formula:C₃₁H₂₅ClFN₃O
Molecular Weight:510.01
Hs Code.:

Synonyms:N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

Suppliers and Price of N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

Chemical Property:

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Technology Process of N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

There total 1 articles about N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 163009-06-1
[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetic acid

: 15205-11-5
2-chloro-4-fluorobenzylamine

: 1082828-00-9
N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

Guidance literature:: With N-ethylmorpholine;; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 18h;

Reference yield:

: 1082828-00-9
N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

: 1082827-96-0
N-[(2-chloro-4-fluorophenyl)methyl]-2-(1H-pyrazol-4-yl)acetamide

Guidance literature:: N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 18h;

With water; potassium carbonate; In dichloromethane;

Reference yield:

: 1082828-00-9
N-[(2-chloro-4-fluorophenyl)methyl]-2-[1-(triphenylmethyl)-1H-pyrazol-4-yl]acetamide

: 1082827-09-5
N-[(2-chloro-4-fluorophenyl)methyl]-2-{1-[6-(ethyloxy)-2-pyridinyl]-1H-pyrazol-4-yl}acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 18 h / 20 °C

2: copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine / 1-methyl-pyrrolidin-2-one / 1 h / 180 °C / Microwave irradiation

With copper(l) iodide; potassium carbonate; trifluoroacetic acid; N,N`-dimethylethylenediamine; In 1-methyl-pyrrolidin-2-one; dichloromethane;