Technology Process of (3S,4R)-6-Methyl-2-[2-oxo-2-phenyl-eth-(Z)-ylidene]-4-phenyl-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid diethyl ester
There total 4 articles about (3S,4R)-6-Methyl-2-[2-oxo-2-phenyl-eth-(Z)-ylidene]-4-phenyl-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid diethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
molybdenum hexacarbonyl;
In
water; acetonitrile;
for 23h;
Heating;
DOI:10.1021/jm00403a030
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 5.1 percent / triethylamine, phosphorous oxychloride / CHCl3 / Heating
2: lithium diisopropylamide / tetrahydrofuran / -78 °C
3: 16 percent / molybdenum hexacarbonyl / acetonitrile; H2O / 23 h / Heating
With
molybdenum hexacarbonyl; triethylamine; lithium diisopropyl amide; trichlorophosphate;
In
tetrahydrofuran; chloroform; water; acetonitrile;
DOI:10.1021/jm00403a030
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 6.9 g / hydroxylamine hydrochloride / pyridine / 1.) room temperature, 20 min, 2.) reflux, 1 h
2: lithium diisopropylamide / tetrahydrofuran / -78 °C
3: 16 percent / molybdenum hexacarbonyl / acetonitrile; H2O / 23 h / Heating
With
molybdenum hexacarbonyl; hydroxylamine hydrochloride; lithium diisopropyl amide;
In
tetrahydrofuran; pyridine; water; acetonitrile;
DOI:10.1021/jm00403a030
