3590-37-2

Usage

Uses

Used in Organic Synthesis:
ETHYL 3-NITROPROPANOATE is used as a reagent in organic synthesis for the preparation of various other organic compounds. Its versatility in chemical reactions makes it a valuable component in the synthesis of a wide range of products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, ETHYL 3-NITROPROPANOATE is utilized in the production of various medications. Its chemical properties allow it to be a key intermediate in the synthesis of pharmaceutical compounds, contributing to the development of new drugs.
Used as a Flavoring Agent in the Food Industry:
ETHYL 3-NITROPROPANOATE is employed as a flavoring agent in the food industry due to its fruity aroma. Its ability to impart a pleasant scent and taste to food products makes it a sought-after ingredient in the creation of flavor profiles for various food items.

InChI:InChI=1/C5H9NO4/c1-2-10-5(7)3-4-6(8)9/h2-4H2,1H3

Upstream product

• 6414-69-3 ethyl 3-iodopropanoate 
• 539-74-2 Ethyl 3-bromopropionate 
• 27374-25-0 [(1-Ethoxycyclopropyl)oxy]trimethylsilane 
• 64-17-5 ethanol 
• 504-88-1 3-nitropropionic acid 
• 5941-50-4 (E)-ethyl 3-nitroacrylate 
• 1851-84-9 ethyl 2-hydroxy-3-nitropropanoate 
• 1193-10-8 3-methyl-2,5-dihydrothiophen-1,1-dioxide 
• 5941-50-4 ethyl β-nitroacrylate 
• 122876-02-2 ethyl 3-nitro-3-(phenylsulfonyl)propionate 

Downstream Products

• 86988-58-1 3-[(3-Methoxy-phenyl)-hydrazono]-3-nitro-propionic acid ethyl ester 
• 3929-70-2 ethyl 5-phenyl-3-isoxazoleacetate 
• 79852-93-0 3-Nitro-3-(phenyl-hydrazono)-propionic acid ethyl ester 
• 86988-59-2 3-[(3,5-Dimethoxy-phenyl)-hydrazono]-3-nitro-propionic acid ethyl ester 
• 77802-23-4 3-Nitro-2-naphthoesaeure-aethylester 
• 114957-70-9 (3S,4R)-6-Methyl-2-[2-oxo-2-phenyl-eth-(Z)-ylidene]-4-phenyl-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 114957-77-6 2-Acetyl-3-phenyl-4-(5-phenyl-isoxazol-3-yl)-pentanedioic acid diethyl ester 
• 114978-18-6 (2Z,3α,4β)-(+/-)-diethyl 1,2,3,4-tetrahydro-6-methyl-2-(2-oxo-2-phenylethylidene)-4-<2-(trifluoromethyl)phenyl>-3,5-pyridinedicarboxylate 
• 114957-76-5 diethyl 2-acetyl-4-(5-phenyl-3-isoxazolyl)-3-<2-(trifluoromethyl)phenyl>pentanedioate 
• 73428-03-2 3-Nitro-2-naphthoesaeure 

Relevant academic research and scientific papers

Pyrrolo[2,1-c][1,4]naphthodiazepine Linked Piperazine Compounds and a Process for the Preparation Thereof

The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R=R′=(Formula II). n=1-9 and R″=methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl

NUCLEIC ACID BINDING COMPOUNDS, METHODS OF MAKING, AND USE THEREOF

The present invention relates to oligomer compounds, including dimers and trimers, formed by a disulfide, sulfinyl thio, olefin or hydrocarbon bond, or a hydrazone exchange bond between two or more monomers. Methods of making the monomers and the oligomers is also disclosed. Use of the compounds for inhibiting the activity of target RNA molecules, particularly those having a secondary structure that include a stem or stem-loop formation. Dimer compounds capable of inhibiting the activity of an HIV-1 RNA frameshifting stem-loop and a (CUG)n expanded repeat stem- loop are disclosed, as are methods of treating diseases associated with these target RNA molecules.

PYRROLO [2,1-C]1,4]NAPHTHODIAZEPINE LINKED PIPERAZINE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF

The present invention provides a compound of general formula A, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]naphthodiazepine linked substituted piperazine conjugates attached through different alkane spacers of general formula A. (Formula I) General formula A. Where R= R'= (Formula II). n=1-9 and R''= methyl, ethyl, acetyl, benzyl, piperinoyl, 4-fluorophenyl, 4-chlorophenyl, 4-methoxyphenyl, pyridyl, pyrimidyl

Diastereoselective synthesis of 1,3,5- Trisubstituted 4-nitropyrrolidin-2- ones via a nitro-mannich/lactamization cascade

A versatile one-pot nitro-Mannich/lactamization cascade for the direct synthesis of 1,3,5-trisubstituted 4-nitropyrrolidin-2-ones has been developed. The reaction is easy to perform and broad in scope, and high levels of diastereoselectivity can be achiev

Cascade formation of isoxazoles: Facile base-mediated rearrangement of substituted oxetanes

Give me five! Nitro compounds and oxetan-3-one react through an intriguing cascade sequence to give isoxazole-4-carbaldehydes using inexpensive reagents in a one-pot procedure (see scheme; Ms=methanesulfonyl). A variety of 3-substituted isoxazole-4-carbaldehydes were obtained in high overall yields.

Synthesis and structure of nitrocyclohexenylcarboxylates

The diene condensation of 3-nitro- and 3-bromo-3-nitroacrylates with 2,3-dimethyl-1,3-butadiene and isoprene obtained under the reaction condition from 3-methyl-3-thiolene-1,1-dioxide was investigated. The formed 6-nitro-3-cyclohexenylcarboxylates were subjected to the intramolecular transformation (dehydration and dehydrohalogenation) to give the corresponding nitrocyclohexadienyl- and arylcarboxylates. The structure of the obtained compounds was established from the IR, 1H NMR spectra and independent synthesis.

Synthesis of 3-nitropropanol homologues

Several high yielding routes to oxygenated nitropropanes have been developed that include a palladium catalyzed nitro allylation of allylic carbonates, nitration of brominated compounds and a nitro aldol condensation/hydrogenation sequence. Georg Thieme Verlag Stuttgart.

4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as potent Src kinase inhibitors

It has been previously reported that appropriately substituted 4-anilinoquinoline-3-carbonitriles are potent inhibitors of Src kinase, with biological activity in vitro and in vivo. Structural modifications to these compounds have been explored, providing

Arylmethyl radicals from arylmethoxybromodiazirines

(Chemical Equation Presented) Photolytic decompositions of 3-arylmethoxy-3-bromodiazirines afford arylmethyl radicals by homolyses of the diazirines' excited states.

Tricyclic protein kinase inhibitors

This invention provides compounds of formula 1, having the structure which are useful as inhibitors of protein tyro sine kinase and are antiproliferative agents.