1-Benzyl-4-(4-bromo-2-nitrophenyl)piperazine

Base Information

Chemical Name:1-Benzyl-4-(4-bromo-2-nitrophenyl)piperazine
CAS No.:883522-59-6
Molecular Formula:C17H18 Br N3 O2
Molecular Weight:376.25
Hs Code.:2933599090
DSSTox Substance ID:DTXSID30429144
Mol file:883522-59-6.mol

Synonyms:883522-59-6;4-bromo-2-nitro-(4-benzyl-1-piperazino)-benzene;1-benzyl-4-(4-bromo-2-nitrophenyl)piperazine;3-NITRO-4-(4-BENZYL-1-PIPERAZINO)BROMOBENZENE;DTXSID30429144;AKOS006487261;4-Bromo-2-nitro-(4-benzyl-1-piperazine)benzene

Suppliers and Price of 1-Benzyl-4-(4-bromo-2-nitrophenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Bromo-2-nitro-(4-benzyl-1-piperazino)-benzene 98%
500mg
$ 139.00

Labseeker
3-NITRO-4-(4-BENZYL-1-PIPERAZINO)BROMOBENZENE 95
25g
$ 2658.00

Labseeker
3-NITRO-4-(4-BENZYL-1-PIPERAZINO)BROMOBENZENE 95
10g
$ 1467.00

American Custom Chemicals Corporation
3-NITRO-4-(4-BENZYL-1-PIPERAZINO)BROMOBENZENE 95.00%
500MG
$ 729.96

AK Scientific
4-Bromo-2-nitro-(4-benzyl-1-piperazino)-benzene
500mg
$ 237.00

Total 7 raw suppliers

Chemical Property of 1-Benzyl-4-(4-bromo-2-nitrophenyl)piperazine

Chemical Property:

Boiling Point:483.3±45.0 °C(Predicted)
PKA:7.17±0.10(Predicted)
PSA：52.30000
Density:1.452±0.06 g/cm3(Predicted)
LogP:4.20560
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:375.05824
Heavy Atom Count:23
Complexity:390

Purity/Quality:

98%min ^*data from raw suppliers

4-Bromo-2-nitro-(4-benzyl-1-piperazino)-benzene 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)C3=C(C=C(C=C3)Br)[N+](=O)[O-]

Technology Process of 1-Benzyl-4-(4-bromo-2-nitrophenyl)piperazine

There total 1 articles about 1-Benzyl-4-(4-bromo-2-nitrophenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 2759-28-6
1-phenylmethylpiperazine

: 3460-18-2
1,4-dibromo-2-nitrobenzene

: 883522-59-6
1-benzyl-4-(4-bromo-2-nitro-phenyl)-piperazine

Guidance literature:: In isopropyl alcohol; at 70 ℃; for 24h;
DOI:10.1021/jm0602864

Reference yield: 95.0%

: 883522-59-6
1-benzyl-4-(4-bromo-2-nitro-phenyl)-piperazine

: 883908-27-8
1-benzyl-4-(2-amino-4-bromo-phenyl)-piperazine

Guidance literature:: With sodium dithionate; sodium carbonate; In methanol; water; at 70 ℃;
DOI:10.1016/j.bmc.2013.01.064

Reference yield:

: 883522-59-6
1-benzyl-4-(4-bromo-2-nitro-phenyl)-piperazine

: 474330-93-3
naphthalene-1-carboxylic acid (5-bromo-2-piperazin-1-yl-phenyl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / Zn; aq. KH₂PO₄ / tetrahydrofuran / 24 h / 80 °C

2: 75 percent / DIEA / CH₂Cl₂ / 4 h / 20 °C

3: 97 percent / ammonium formate / Pd/C / methanol / 6 h / Heating

With potassium dihydrogenphosphate; ammonium formate; N-ethyl-N,N-diisopropylamine; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm0602864