4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

Base Information

Chemical Name:4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate
CAS No.:1411775-07-9
Molecular Formula:C₂H₄O₂*C₁₄H₁₇N₃O₄
Molecular Weight:351.359
Hs Code.:

Synonyms:4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

Suppliers and Price of 4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

There total 5 articles about 4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1411775-05-7
4-{4-[(5R)-5-[(dibenzylamino)methyl]-2-oxo-1,3-oxazolidine-3-yl]phenyl}morpholine-3-one

: 64-19-7,77671-22-8
acetic acid

: 1411775-07-9
4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; at 20 ℃; for 24h; under 7500.75 Torr;

Reference yield:

: 438056-69-0
4-(4-aminophenyl)morpholin-3-one

: 1411775-07-9
4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

Guidance literature:: Multi-step reaction with 5 steps

1: acetonitrile; water / 50 - 55 °C

2: 1-methyl-pyrrolidin-2-one / toluene / 0.33 h / 80 - 82 °C

3: sodium iodide / acetonitrile / 37 h / Reflux

4: caesium carbonate / 35 h / 80 °C

5: hydrogen / palladium 10% on activated carbon / 24 h / 20 °C / 7500.75 Torr

With 1-methyl-pyrrolidin-2-one; hydrogen; caesium carbonate; sodium iodide; palladium 10% on activated carbon; In water; toluene; acetonitrile;

Reference yield:

: 1252018-21-5
(S)-4-[4-[(3-chloro-2-hydroxypropyl)amino]phenyl]-3-morpholinone

: 1411775-07-9
4-{4-[(5R)-aminomethyI-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morphoIine-3-one acetate

Guidance literature:: Multi-step reaction with 4 steps

1: 1-methyl-pyrrolidin-2-one / toluene / 0.33 h / 80 - 82 °C

2: sodium iodide / acetonitrile / 37 h / Reflux

3: caesium carbonate / 35 h / 80 °C

4: hydrogen / palladium 10% on activated carbon / 24 h / 20 °C / 7500.75 Torr

With 1-methyl-pyrrolidin-2-one; hydrogen; caesium carbonate; sodium iodide; palladium 10% on activated carbon; In toluene; acetonitrile;