1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on

Base Information

• Chemical Name: 1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on
• CAS No.: 154185-95-2
• Molecular Formula: C₂₉H₂₀Br₂N₄OS₂
• Molecular Weight: 664.444
• Mol file: 154185-95-2.mol

Synonyms:1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on

Chemical Property of 1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on

There total 1 articles about 1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-Mercapto-4-(4-bromphenyl)-6-methyl-pyridin-3-carbonitril (94639-15-3) + 1,3-Dichloroacetone (534-07-6) → 1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on (154185-95-2)

Guidance literature:

With triethylamine; In methanol; for 0.25h; Ambient temperature;

DOI:10.1002/ardp.19933261209

Reference yield: 86.0%

1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on (154185-95-2) → Bis<3-amino-4-(4-bromphenyl)-6-methylthieno<2,3-b>pyridin-2-yl>keton (154186-00-2)

Guidance literature:

With methanol; sodium; for 1h; Heating;

DOI:10.1002/ardp.19933261209

Reference yield:

1,3-Bis<4-(4-bromphenyl)-3-cyan-6-methylpyridin-2-ylthio>propan-2-on (154185-95-2) → 4,6-Bis(4-bromphenyl)-5H-2,8-dimethylbispyrido<3',2':4,5>thieno<2,3-b:2',3'-e>pyridin-11-on

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / Na/MeOH / 1 h / Heating

2: 69 percent / 85percent H₃PO₄ / 2 h / Heating

With methanol; phosphoric acid; sodium;

DOI:10.1002/ardp.19933261209

upstream raw materials:

2-Mercapto-4-(4-bromphenyl)-6-methyl-pyridin-3-carbonitril

1,3-Dichloroacetone

Downstream raw materials:

Bis<3-amino-4-(4-bromphenyl)-6-methylthieno<2,3-b>pyridin-2-yl>keton