3-(acetyloxy)chol-5-en-24-oic acid

Base Information

• Chemical Name: 3-(acetyloxy)chol-5-en-24-oic acid
• CAS No.: 19462-13-6
• Molecular Formula: C26H40 O4
• Molecular Weight: 416.601
• Mol file: 19462-13-6.mol

Synonyms:Chol-5-en-24-oicacid, 3b-hydroxy-, acetate (8CI);Chol-5-enic acid, 3b-hydroxy-, acetate (6CI,7CI); 3b-Acetoxychol-5-en-24-oic acid; 3b-Acetoxychol-5-enoic acid; NSC226154

Chemical Property of 3-(acetyloxy)chol-5-en-24-oic acid

Chemical Property:

• Vapor Pressure: 1.22E-12mmHg at 25°C
• Boiling Point: 529.8°C at 760 mmHg
• Flash Point: 170.2°C
• Density: 1.11g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(acetyloxy)chol-5-en-24-oic acid

There total 14 articles about 3-(acetyloxy)chol-5-en-24-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3β-hydroxy-5-cholenoic acid (5255-17-4) + acetic anhydride (108-24-7) → 3β-acetoxy-5-cholenic acid (19462-13-6)

Guidance literature:

With pyridine;

DOI:10.1016/S0022-1139(01)00409-2

Reference yield: 74.2%

3β-acetoxy-Δ5-cholenic aldehyde (86476-29-1) → 3β-acetoxy-5-cholenic acid (19462-13-6)

Guidance literature:

With chromic acid; In tetrahydrofuran; at 0 ℃; for 0.166667h;

DOI:10.1016/0040-4020(82)80080-X

Reference yield:

3β-acetoxy-5α,6β-dibromocholestane (514-50-1) → 3β-acetoxy-5-cholenic acid (19462-13-6)

Guidance literature:

With chromium(VI) oxide; acetic acid; Erwaermen des Reaktionsprodukts mit Zink-Pulver und Essigsaeure und Erwaermen des erhaltenen Reaktionsprodukts mit wss. Natronlauge;

DOI:10.1021/ja01311a036 DOI:10.1021/ja01851a038 DOI:10.1002/hlca.193501801132

upstream raw materials:

3β-acetoxy-5α,6β-dibromocholestane

3β-hydroxy-5-cholenoic acid

acetic anhydride

3β-acetoxy-Δ⁵-cholenic aldehyde

Downstream raw materials:

methyl 3β-acetoxychol-5-en-24-oate

24,24-diphenyl-cholene-(5)-diol-(3β,24)

dehydroepiandrosterone

3β,24-dihydroxychol-5-ene