Technology Process of (2S,3R,4R,5S)-5-amino-N-diphenylmethylene-4-pivaloyloxy-2,3,4-trihydroxy-hexan-1-al
There total 5 articles about (2S,3R,4R,5S)-5-amino-N-diphenylmethylene-4-pivaloyloxy-2,3,4-trihydroxy-hexan-1-al which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hypochlorite; TEMPO; sodium hydrogencarbonate;
tetrabutyl-ammonium chloride; potassium bromide;
In
dichloromethane; water;
DOI:10.1021/jo9820115
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 89 percent / 4-(dimethylamino)pyridine; pyridine / 48 h
2.1: K3Fe(CN)6; K2CO3; CH3SO2NH2 / K2OsO2(OH)4 / H2O; 2-methyl-propan-2-ol / 20 °C
2.2: 50 percent / Na2SO3 / 2-methyl-propan-2-ol; H2O / 0.33 h
3.1: 90 percent / nBu4NF / tetrahydrofuran / 3 h / 20 °C
4.1: 2,2,6,6-tetramethylpiperidine-N-oxide; NaOCl; NaHCO3 / KBr; tetrabutylammonium chloride hydrate / CH2Cl2; H2O
With
pyridine; dmap; sodium hypochlorite; TEMPO; methanesulfonamide; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; potassium carbonate; potassium hexacyanoferrate(III);
potassium dioxotetrahydroxoosmate(VI); tetrabutyl-ammonium chloride; potassium bromide;
In
tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;
1.1: Acylation / 2.1: osmylation / 2.2: Hydrolysis / 3.1: Hydrolysis / 4.1: Oxidation;
DOI:10.1021/jo9820115
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 89 percent / 4-(dimethylamino)pyridine; pyridine / 48 h
2.1: K3Fe(CN)6; K2CO3; CH3SO2NH2 / K2OsO2(OH)4 / H2O; 2-methyl-propan-2-ol / 20 °C
2.2: 50 percent / Na2SO3 / 2-methyl-propan-2-ol; H2O / 0.33 h
3.1: 90 percent / nBu4NF / tetrahydrofuran / 3 h / 20 °C
4.1: 2,2,6,6-tetramethylpiperidine-N-oxide; NaOCl; NaHCO3 / KBr; tetrabutylammonium chloride hydrate / CH2Cl2; H2O
With
pyridine; dmap; sodium hypochlorite; TEMPO; methanesulfonamide; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; potassium carbonate; potassium hexacyanoferrate(III);
potassium dioxotetrahydroxoosmate(VI); tetrabutyl-ammonium chloride; potassium bromide;
In
tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;
1.1: Acylation / 2.1: osmylation / 2.2: Hydrolysis / 3.1: Hydrolysis / 4.1: Oxidation;
DOI:10.1021/jo9820115
