(3-methoxylphenyl)diphenylphosphine oxide

Base Information

• Chemical Name: (3-methoxylphenyl)diphenylphosphine oxide
• CAS No.: 95278-09-4
• Molecular Formula: C₁₉H₁₇O₂P
• Molecular Weight: 308.317
• Mol file: 95278-09-4.mol

Synonyms:(3-methoxylphenyl)diphenylphosphine oxide

Chemical Property of (3-methoxylphenyl)diphenylphosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (3-methoxylphenyl)diphenylphosphine oxide

There total 23 articles about (3-methoxylphenyl)diphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(3-methoxyphenyl)(diphenyl)phosphane (13145-84-1) → (3-methoxylphenyl)diphenylphosphine oxide (95278-09-4)

Guidance literature:

With dihydrogen peroxide; In methanol; for 1h; Ambient temperature;

DOI:10.1002/hlca.19910740215

Reference yield: 95.0%

3-methoxyphenyl bromide (2398-37-0) + Diphenylphosphine oxide (4559-70-0) → (3-methoxylphenyl)diphenylphosphine oxide (95278-09-4)

Guidance literature:

With [2,2]bipyridinyl; nickel(II) chloride hexahydrate; zinc; In water; at 70 ℃; for 15h;

DOI:10.1021/ol201141m

Reference yield: 81.0%

1-methoxy-3-methylsulfanyl-benzene (2388-74-1) + Diphenylphosphine oxide (4559-70-0) → (3-methoxylphenyl)diphenylphosphine oxide (95278-09-4)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; sodium t-butanolate; In 1,4-dioxane; at 100 ℃; for 18h; Schlenk technique; Inert atmosphere; Glovebox;

DOI:10.1039/c6cc06048j

upstream raw materials:

(3-methoxyphenyl)(diphenyl)phosphane

2-(diphenylphosphinyl)-6-methoxyphenyl triflate

3-methoxyphenyl bromide

chloro-diphenylphosphine

Downstream raw materials:

(3-hydroxyphenyl)diphenylphosphine oxide

(3-methoxyphenyl)(diphenyl)phosphane

(Ra)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine oxide)

(RS)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine oxide)

Refernces

• 1、 Henyecz, Réka,Huszár, Bianka,Keglevich, Gy?rgy,Mucsi, Zoltán. "Microwave assisted P–C coupling reactions without directly added P-ligands". . . Retrieved 2021/12/24.
• 2、 Yang, Jia,Xiao, Jing,Chen, Tieqiao,Yin, Shuang-Feng,Han, Li-Biao. "Efficient nickel-catalyzed phosphinylation of C-S bonds forming C-P bonds". supporting information. p. 12233 - 12236. Retrieved 2016/10/21.