1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone

Base Information

• Chemical Name: 1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone
• CAS No.: 170469-82-6
• Molecular Formula: C₁₃H₁₄O₂S₂
• Molecular Weight: 266.385
• Mol file: 170469-82-6.mol

Synonyms:1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone

Chemical Property of 1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone

There total 3 articles about 1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-((E)-1-Acetyl-2-hydroxy-propenylsulfanyl)-isoindole-1,3-dione (152420-82-1) + phenylthioethylene (1822-73-7) → 1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone (170469-82-6)

Guidance literature:

With pyridine; In chloroform; for 63h; Ambient temperature;

DOI:10.1021/jo00125a030

Reference yield:

4-trimethylsiloxy-3-penten-2-one (13257-81-3) → 1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone (170469-82-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / -18 °C

2: 79 percent / pyridine / CHCl₃ / 63 h / Ambient temperature

With pyridine; In chloroform; acetic acid;

DOI:10.1021/jo00125a030

Reference yield:

acetylacetone (123-54-6,81235-32-7) → 1-(5,6-dihydro-2-methyl-6-(phenylthio)-1,4-oxathiin-3-yl)ethanone (170469-82-6)

Guidance literature:

Multi-step reaction with 2 steps

1: CH₂Cl₂ / Ambient temperature

2: 79 percent / pyridine / CHCl₃ / 63 h / Ambient temperature

With pyridine; In dichloromethane; chloroform;

DOI:10.1021/jo00125a030

upstream raw materials:

2-((E)-1-Acetyl-2-hydroxy-propenylsulfanyl)-isoindole-1,3-dione

phenylthioethylene

4-trimethylsiloxy-3-penten-2-one

acetylacetone