Methyl 2-[(4-aminophenyl)formamido]acetate

Base Information

Chemical Name:Methyl 2-[(4-aminophenyl)formamido]acetate
CAS No.:5259-86-9
Molecular Formula:C10H12N2O3
Molecular Weight:208.217
Hs Code.:2924299090
DSSTox Substance ID:DTXSID30875960
Nikkaji Number:J1.586.229G
Wikidata:Q82857451
ChEMBL ID:CHEMBL3278336
Mol file:5259-86-9.mol

Synonyms:5259-86-9;methyl 2-[(4-aminophenyl)formamido]acetate;methyl 2-[(4-aminobenzoyl)amino]acetate;METHYL[(4-AMINOBENZOYL)AMINO]ACETATEHYDROCHLORIDE;methyl-p-amino-hippurate;CHEMBL3278336;SCHEMBL10528940;DTXSID30875960;methyl N-(4-aminobenzoyl)glycinate;AKOS003624987;Methyl [(4-aminobenzoyl)amino]acetate;P-AMINOHIPPURIC ACID, ME ESTER;CS-0246800;EN300-34384;[(4-Aminobenzoyl)amino]acetic acid methyl ester

Suppliers and Price of Methyl 2-[(4-aminophenyl)formamido]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
methyl2-[(4-aminophenyl)formamido]acetate
250mg
$ 265.00

AK Scientific
Methyl[(4-aminobenzoyl)amino]acetatehydrochloride
500mg
$ 349.00

Total 10 raw suppliers

Chemical Property of Methyl 2-[(4-aminophenyl)formamido]acetate

Chemical Property:

Vapor Pressure:1.19E-07mmHg at 25°C
Melting Point:130-131 °C
Refractive Index:1.568
Boiling Point:431.5 °C at 760 mmHg
PKA:13.87±0.46(Predicted)
Flash Point:214.8 °C
PSA：81.42000
Density:1.235 g/cm³
LogP:1.94570
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:208.08479225
Heavy Atom Count:15
Complexity:235

Purity/Quality:

99% ^*data from raw suppliers

methyl2-[(4-aminophenyl)formamido]acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)CNC(=O)C1=CC=C(C=C1)N

Technology Process of Methyl 2-[(4-aminophenyl)formamido]acetate

There total 5 articles about Methyl 2-[(4-aminophenyl)formamido]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 2644-96-4
2-(4-nitrobenzamido)acetic acid methyl ester

: 5259-86-9
(4-amino-benzoylamino)-acetic acid methyl ester

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 5h;
DOI:10.1021/acs.jmedchem.5b00775

Reference yield: 71.0%

: 5680-79-5,883886-67-7
glycine ethyl ester hydrochloride

: 540-37-4
p-aminoiodobenzene

: 13939-06-5,199620-15-0
molybdenum hexacarbonyl

: 5259-86-9
(4-amino-benzoylamino)-acetic acid methyl ester

Guidance literature:: With C₃₅H₂₀F₃₄NO₃^(1-)*Pd⁽²⁺⁾*Cl^(1-); N-ethyl-N,N-diisopropylamine; In water; at 110 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1016/j.tet.2014.09.065

Reference yield:

: 122-04-3
4-nitro-benzoyl chloride

: 5259-86-9
(4-amino-benzoylamino)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 15 h / 0 - 20 °C

2: hydrogen; palladium on activated charcoal / methanol / 5 h / 20 °C

With palladium on activated charcoal; hydrogen; potassium carbonate; In methanol; acetonitrile;
DOI:10.1021/acs.jmedchem.5b00775