N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide

Base Information

• Chemical Name: N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide
• CAS No.: 304862-38-2
• Molecular Formula: C₂₃H₂₆N₂O₄S
• Molecular Weight: 426.536
• Mol file: 304862-38-2.mol

Synonyms:N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide

Chemical Property of N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide

There total 1 articles about N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

cis-2-(4-chloro-2-butenyl)-1H-isoindole-1,3(2H)-dione (84347-67-1) + N-ethyl-(2-mesitylene)sulfonamide (151915-07-0) → N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide (304862-38-2)

Guidance literature:

N-ethyl-(2-mesitylene)sulfonamide; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

cis-2-(4-chloro-2-butenyl)-1H-isoindole-1,3(2H)-dione; In N,N-dimethyl-formamide; at 80 ℃; for 18h; Further stages.;

DOI:10.1021/jm000310s

Reference yield: 65.0%

N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide (304862-38-2) → N-ethyl-N-(4-amino-2-butenyl)mesitylenesulfonamide (328587-61-7)

Guidance literature:

With hydrazine; In methanol; at 55 ℃; for 24h;

DOI:10.1021/jm000310s

Reference yield:

N-ethyl-N-(4-phthalimido-2-butenyl)mesitylenesulfonamide (304862-38-2) → N3,N8,N13,N18,N23-pentakis(mesitylenesulfonyl)-3,8,13,18,23-pentaaza-(5Z,10Z,20Z)-pentacosatriene (304862-73-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 65 percent / H₂NNH₂ / methanol / 24 h / 55 °C

2.1: 96 percent / aq. KOH / dioxane / 20 °C

3.1: NaH / dimethylformamide / 2 h / 20 °C

3.2: 70 percent / dimethylformamide / 18 h / 50 °C

4.1: NaH / dimethylformamide / 2 h / 20 °C

4.2: 82 percent / dimethylformamide / 18 h / 50 °C

With potassium hydroxide; sodium hydride; hydrazine; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;

DOI:10.1021/jm000310s

upstream raw materials:

cis-2-(4-chloro-2-butenyl)-1H-isoindole-1,3(2H)-dione

N-ethyl-(2-mesitylene)sulfonamide

Downstream raw materials:

N-ethyl-N-(4-amino-2-butenyl)mesitylenesulfonamide

N¹,N⁴-bis(mesitylenesulfonyl)-N⁴-ethyl-1,4-diamino-2-butene

N³,N⁸-bis(mesitylenesulfonyl)-12-chloro-3,8-diaza-(5Z,10Z)-dodecadiene

N³,N⁸-bis(mesitylenesulfonyl)-12-iodo-3,8-diaza-(5Z)-dodecane