isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate

Base Information

Chemical Name:isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate
CAS No.:1436855-46-7
Molecular Formula:C₁₈H₂₄N₂O₃
Molecular Weight:316.4
Hs Code.:

Synonyms:isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate

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Chemical Property of isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate

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Technology Process of isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate

There total 3 articles about isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 13361-30-3
isopropyl cyanoacetate

: 513-86-0,52217-02-4,51555-24-9
3-hydroxy-2-butanon

: 2393-23-9
4-methoxy-benzylamine

: 1436855-46-7
isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate

Guidance literature:: 3-hydroxy-2-butanon; 4-methoxy-benzylamine; In cyclohexane; for 2h; Reflux; Dean-Stark;

isopropyl cyanoacetate; at 0 ℃; for 2h; Reflux; Dean-Stark;

Reference yield:

: 13361-30-3
isopropyl cyanoacetate

: C₁₂H₁₇NO₂

: 1436855-46-7
isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate

Guidance literature:: In cyclohexane; at 0 ℃; for 2h; Dean-Stark; Reflux;

Reference yield:

: 2393-23-9
4-methoxy-benzylamine

: 1436855-46-7
isopropyl 2-amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrolo-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: cyclohexane / 2 h / Dean-Stark; Reflux

2: cyclohexane / 2 h / 0 °C / Dean-Stark; Reflux

In cyclohexane;