((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

Base Information

Chemical Name:((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol
CAS No.:1383568-90-8
Molecular Formula:C₃₀H₃₂N₂O₄S
Molecular Weight:516.661
Hs Code.:

Synonyms:((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

Suppliers and Price of ((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

There total 7 articles about ((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1383568-89-5
(S,E)-3-ethylidene-1-(4-methoxybenzyl)piperidine-4-carbaldehyde

: 40900-03-6
1-(benzenesulfonyl)-2-lithioindole

: 1383568-90-8
((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

Guidance literature:: In tetrahydrofuran;
DOI:10.1038/nchem.1050

Reference yield:

: 1312678-77-5
(S)-1-(N-(4-methoxybenzyl)-1,2,5,6-tetrahydropyridin-3-yl)ethanol

: 1383568-90-8
((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

Guidance literature:: Multi-step reaction with 4 steps

1: potassium hydride / tetrahydrofuran

2: n-butyllithium / tetrahydrofuran

4: tetrahydrofuran

With n-butyllithium; potassium hydride; In tetrahydrofuran; 2: Wittig rearrangement / 3: Parikh-Doering oxidation;
DOI:10.1038/nchem.1050

Reference yield:

: 1383568-86-2
(S)-1-(4-methoxybenzyl)-5-(1-((tributylstannyl)methoxy)ethyl)-1,2,3,6-tetrahydropyridine

: 1383568-90-8
((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1: n-butyllithium / tetrahydrofuran

3: tetrahydrofuran

With n-butyllithium; In tetrahydrofuran; 1: Wittig rearrangement / 2: Parikh-Doering oxidation;
DOI:10.1038/nchem.1050