7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

Base Information

Chemical Name:7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
CAS No.:1040273-60-6
Molecular Formula:C₃₃H₃₄N₄O₄
Molecular Weight:550.657
Hs Code.:

Synonyms:7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

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Chemical Property of 7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

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Technology Process of 7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

There total 14 articles about 7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 2',3',5'-O-tribenzyl-2'-C-methyl-6-methylthio-4-aza-7,9-dideazadenosine

: 1040273-60-6
7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

Guidance literature:: With ammonia; In methanol; at 100 ℃; for 24h;
DOI:10.1016/j.ejmech.2020.112198

Reference yield: 17.8%

: 1040273-59-3
C₃₂H₃₃N₃O₄

: 3473-63-0
formamidine acetic acid

: 1040273-60-6
7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

Guidance literature:: In N,N-dimethyl acetamide; at 140 ℃; for 3h;

Reference yield:

: C₃₈H₄₂N₄O₇

: 1040273-60-6
7-((2S,3S,4R,5R)-3,4-bis-(benzyloxy)-5-benzyloxymethyl-3-methyl-tetrahydrofuran-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine

Guidance literature:: C₃₈H₄₂N₄O₇; With triethylsilane; In dichloromethane; at 0 ℃; for 0.0833333h; Inert atmosphere;

With boron trifluoride diethyl etherate; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;