C₄₄H₅₀O₉Si

Base Information

• Chemical Name: C₄₄H₅₀O₉Si
• CAS No.: 123358-25-8
• Molecular Formula: C₄₄H₅₀O₉Si
• Molecular Weight: 750.961
• Mol file: 123358-25-8.mol

Synonyms:C₄₄H₅₀O₉Si

Chemical Property of C₄₄H₅₀O₉Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₅₀O₉Si

There total 24 articles about C₄₄H₅₀O₉Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N-methyl-N-trimethylsilyl-2,2,2-trifluoroacetamide (24589-78-4) + C41H42O9 → C44H50O9Si (123358-25-8)

Guidance literature:

With dmap; In acetonitrile;

DOI:10.1021/ja00206a050

Reference yield:

C27H38O8 (77573-38-7) → C44H50O9Si (123358-25-8)

Guidance literature:

Multi-step reaction with 11 steps

1: MnO₂ / CH₂Cl₂

2: H₂ / Pt/C / ethyl acetate / 760 Torr

3: 1.) ArSeCN, (n-Bu)3P, 2.) m-CPBA / 1.) THF, room temp., 2.) CH₂Cl₂, -78 deg C

4: KCN / methanol

5: DMAP / CH₂Cl₂

6: 1.) DIBAH, 2.) DMAP / 1.) toluene, 2.) pyridine, CH₂Cl₂

7: 50 percent / SeO₂, t-BuOOH / CH₂Cl₂ / 0 °C

8: 1.) SOCl₂, propylene oxide, 2.) KOBz, DMAP / 1.) Et₂O, 2.) CH₃CN

9: HClO₄, Montmorillonite clay (K₁₀) / methanol; ethane-1,2-diol

10: 80 percent / SO₃*pyr*Et₃N / dimethylsulfoxide

11: 91 percent / DMAP / acetonitrile

With tert.-butylhydroperoxide; dmap; potassium cyanide; manganese(IV) oxide; selenium(IV) oxide; thionyl chloride; perchloric acid; pyridine-SO₃ complex; tributylphosphine; Montmorillonite clay (K₁₀); hydrogen; Potassium benzoate; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; methyloxirane; platinum on activated charcoal; In methanol; dichloromethane; ethylene glycol; dimethyl sulfoxide; ethyl acetate; acetonitrile;

DOI:10.1021/ja00206a050

Reference yield:

C27H36O8 (123358-28-1) → C44H50O9Si (123358-25-8)

Guidance literature:

Multi-step reaction with 10 steps

1: H₂ / Pt/C / ethyl acetate / 760 Torr

2: 1.) ArSeCN, (n-Bu)3P, 2.) m-CPBA / 1.) THF, room temp., 2.) CH₂Cl₂, -78 deg C

3: KCN / methanol

4: DMAP / CH₂Cl₂

5: 1.) DIBAH, 2.) DMAP / 1.) toluene, 2.) pyridine, CH₂Cl₂

6: 50 percent / SeO₂, t-BuOOH / CH₂Cl₂ / 0 °C

7: 1.) SOCl₂, propylene oxide, 2.) KOBz, DMAP / 1.) Et₂O, 2.) CH₃CN

8: HClO₄, Montmorillonite clay (K₁₀) / methanol; ethane-1,2-diol

9: 80 percent / SO₃*pyr*Et₃N / dimethylsulfoxide

10: 91 percent / DMAP / acetonitrile

With tert.-butylhydroperoxide; dmap; potassium cyanide; selenium(IV) oxide; thionyl chloride; perchloric acid; pyridine-SO₃ complex; tributylphosphine; Montmorillonite clay (K₁₀); hydrogen; Potassium benzoate; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; methyloxirane; platinum on activated charcoal; In methanol; dichloromethane; ethylene glycol; dimethyl sulfoxide; ethyl acetate; acetonitrile;

DOI:10.1021/ja00206a050

upstream raw materials:

N-methyl-N-trimethylsilyl-2,2,2-trifluoroacetamide

C₂₆H₄₄O₅Si

C₂₈H₄₂O₆

C₂₇H₄₀O₇

Downstream raw materials:

Phorbol

C₄₄H₄₈O₉Si