Ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

Base Information

Chemical Name:Ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate
CAS No.:106809-15-8
Molecular Formula:C₁₁H₈Cl₂FNO₅
Molecular Weight:324.093
Hs Code.:
DSSTox Substance ID:DTXSID601194779

Synonyms:ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate;SCHEMBL10391659;JIVWQBJMHFWMKG-UHFFFAOYSA-N;DTXSID601194779;106809-15-8;ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)-acetate;ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate;ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)-acetate;ethyl (2,4-dichloro-5-fluoro-3-nitro-benzoyl)-acetate;Ethyl 2,4-dichloro-5-fluoro-3-nitro-beta-oxobenzenepropanoate

Suppliers and Price of Ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:322.9763559
Heavy Atom Count:20
Complexity:403

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C1=CC(=C(C(=C1Cl)[N+](=O)[O-])Cl)F

Technology Process of Ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

There total 5 articles about Ethyl(2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106809-14-7
2,4-dichloro-5-fluoro-3-nitro-benzoic acid

: 106809-15-8
ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 91 percent / thionylchloride / 1 h / Heating

2.1: Mg; ethanol; tetrachloromethane / toluene / 2 h / 70 °C

2.2: toluene / 0 - 20 °C

2.3: aq. sulfuric acid / 0 °C

3.1: 23.4 g / p-toluenesulfonic acid / H₂O / 3 h / Heating

With tetrachloromethane; thionyl chloride; ethanol; toluene-4-sulfonic acid; magnesium; In water; toluene;
DOI:10.1128/aac.42.5.1151

Reference yield:

: 106809-16-9
diethyl (2,4-dichloro-5-fluoro-3-nitro-benzoyl)-malonate

: 106809-15-8
ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

Guidance literature:: With toluene-4-sulfonic acid; In water; for 3h; Heating;
DOI:10.1128/aac.42.5.1151

Reference yield:

: 104600-29-5
2,4-dichloro-5-fluoro-3-nitro-benzoyl chloride

: 106809-15-8
ethyl (2,4-dichloro-5-fluoro-3-nitrobenzoyl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: Mg; ethanol; tetrachloromethane / toluene / 2 h / 70 °C

1.2: toluene / 0 - 20 °C

1.3: aq. sulfuric acid / 0 °C

2.1: 23.4 g / p-toluenesulfonic acid / H₂O / 3 h / Heating

With tetrachloromethane; ethanol; toluene-4-sulfonic acid; magnesium; In water; toluene;
DOI:10.1128/aac.42.5.1151