(1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

Base Information

Chemical Name:(1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester
CAS No.:136044-02-5
Molecular Formula:C₂₅H₃₀O₂S
Molecular Weight:394.578
Hs Code.:

Synonyms:(1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

Suppliers and Price of (1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

There total 6 articles about (1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 15082-42-5
lithium benzyloxide

: 136044-01-4
(R)-4-Benzyl-3-[(1S,2R)-4-ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarbonyl]-oxazolidin-2-one

: 136044-02-5
(1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

Guidance literature:: In tetrahydrofuran; at -78 ℃;
DOI:10.1021/jo00020a010

Reference yield:

: 922-63-4
ethylacrolein

: 136044-02-5
(1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1) Mg

2: 100 percent / pyridine, DMAP

3: 71 percent / PdCl₂, PPh₃, K₂CO₃ / dioxane / Heating

4: 50 percent / Me₂AlCl / CH₂Cl₂ / -78 °C

5: 80 percent / tetrahydrofuran / -78 °C

With pyridine; dmap; potassium carbonate; magnesium; triphenylphosphine; palladium dichloride; dimethylaluminum chloride; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1021/jo00020a010

Reference yield:

: 17742-54-0
4-phenylsulfanyl-1-bromobutane

: 136044-02-5
(1S,2R)-4-Ethyl-2-(3-phenylsulfanyl-propyl)-cyclohex-3-enecarboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1) Mg

2: 100 percent / pyridine, DMAP

3: 71 percent / PdCl₂, PPh₃, K₂CO₃ / dioxane / Heating

4: 50 percent / Me₂AlCl / CH₂Cl₂ / -78 °C

5: 80 percent / tetrahydrofuran / -78 °C

With pyridine; dmap; potassium carbonate; magnesium; triphenylphosphine; palladium dichloride; dimethylaluminum chloride; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1021/jo00020a010