5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

Base Information

Chemical Name:5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one
CAS No.:1500092-71-6
Molecular Formula:C₁₈H₁₆N₂O₇S
Molecular Weight:404.4
Hs Code.:

Synonyms:5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

Suppliers and Price of 5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

There total 2 articles about 5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₂H₁₃NO₃

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 1500092-71-6
5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

Guidance literature:: C₁₂H₁₃NO₃; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;

4-Nitrobenzenesulfonyl chloride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1021/jacs.0c00078

Reference yield:

: 3883-94-1
2-amino-4'-methoxyacetophenone hydrochloride

: 1500092-71-6
5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydrogencarbonate / methanol; water

2.1: 0 - 20 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

3.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

With sodium hydride; sodium hydrogencarbonate; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jacs.0c00078

Reference yield: 97.0%

: 2169-69-9
ethyl (E)-2-cyano-3-phenyl-2-propenoate

: 1500092-71-6
5-(4-methoxyphenyl)-3-((4-nitrophenyl)sulfonyl)-5-vinyloxazolidin-2-one

: C₂₉H₂₇N₃O₇S

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; C₆₄H₄₅F₆NP⁽¹⁺⁾*I^(1-); In toluene; at 20 ℃; stereoselective reaction;
DOI:10.1038/nchem.1796