1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Base Information

Chemical Name:1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone
CAS No.:406939-93-3
Molecular Formula:C₄₀H₄₈F₁₈N₈O₆
Molecular Weight:1078.84
Hs Code.:

1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Synonyms:1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Suppliers and Price of 1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
PlerixaforHexatrifluoroacetamide
2.5mg
$ 160.00

Total 4 raw suppliers

Chemical Property of 1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Chemical Property:

Purity/Quality:

NLT 98% ^*data from raw suppliers

PlerixaforHexatrifluoroacetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Plerixafor Hexa(Trifluoroacetic Acid Salt) is a protected Plerixafor; Also, it is derived from 1,4,8,11-tetraazacyclotetradecane Hexa(Trifluoroacetic Acid Salt) (T283955), which is a reagent used in the preparation of Plerixafor derivatives.

Technology Process of 1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

There total 3 articles about 1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 623-25-6
p-Xylylene dichloride

: 406939-92-2
1,1′,1″-(1,4,8,11-tetraazacyclotetradecane-1,4,8-triyl)tris-(2,2,2-trifluoroethan-1-one)

: 406939-93-3
1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Guidance literature:: With potassium iodide; In acetonitrile; Reflux;

Reference yield: 66.0%

: 623-24-5
1,4-bis(bromomethyl)benzene

: 406939-92-2
1,1′,1″-(1,4,8,11-tetraazacyclotetradecane-1,4,8-triyl)tris-(2,2,2-trifluoroethan-1-one)

: 406939-93-3
1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Guidance literature:: With potassium carbonate; In acetonitrile; Reflux;
DOI:10.1016/j.bmc.2009.01.014

Reference yield:

: 295-37-4
1,4,8,11-Tetraazacyclotetradecane

: 406939-93-3
1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylmethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 92.5 percent / Et₃N / methanol / 5 h / 20 °C

2: K₂CO₃ / acetonitrile

With potassium carbonate; triethylamine; In methanol; acetonitrile;
DOI:10.1016/S0040-4039(03)00338-1