2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

Base Information

Chemical Name:2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal
CAS No.:122428-65-3
Molecular Formula:C₁₅H₂₃NO₄
Molecular Weight:281.352
Hs Code.:

Synonyms:2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

Suppliers and Price of 2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

There total 10 articles about 2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 122485-48-7
2S-2-benzyloxyamino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

: 122428-65-3
2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

Guidance literature:: With lithium aluminium tetrahydride; nickel dichloride; In tetrahydrofuran; -78 to -35 deg C, 30 min then room temp., 2.5 h;

Reference yield:

: 50622-10-1
(-)-(2S,3S)-1,4-dimethoxy-2,3-butanediol

: 122428-65-3
2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

Guidance literature:: Multi-step reaction with 6 steps

1: camphorsulfonic acid / neat (no solvent) / 4 h / 40 °C / 1 Torr

2: 95 percent / 5 percent KOH / methanol / 0.17 h / Ambient temperature

3: 1.) oxalyl chloride, DMSO, 2.) triethylamine / 1.) CH₂Cl₂, -60 to -70 deg C, 45 min, 2.) CH₂Cl₂, -60 to -70 deg C

4: methanol; pyridine / 0.25 h / Heating

5: 84 percent / tetrahydrofuran / 0 °C

6: 97 percent / LiAlH₄, NiCl₂ / tetrahydrofuran / -78 to -35 deg C, 30 min then room temp., 2.5 h

With potassium hydroxide; lithium aluminium tetrahydride; oxalyl dichloride; camphor-10-sulfonic acid; dimethyl sulfoxide; triethylamine; nickel dichloride; In tetrahydrofuran; pyridine; methanol;

Reference yield:

: 28203-05-6
dimethoxy-2,2 phenyl-2 ethanol-1

: 122428-65-3
2S-2-amino-1-phenyl-1-propanone (2S,3S)-1,4-dimethoxy-2,3-butylene acetal

Guidance literature:: Multi-step reaction with 7 steps

1: pyridine / 1 h / Ambient temperature

2: camphorsulfonic acid / neat (no solvent) / 4 h / 40 °C / 1 Torr

3: 95 percent / 5 percent KOH / methanol / 0.17 h / Ambient temperature

4: 1.) oxalyl chloride, DMSO, 2.) triethylamine / 1.) CH₂Cl₂, -60 to -70 deg C, 45 min, 2.) CH₂Cl₂, -60 to -70 deg C

5: methanol; pyridine / 0.25 h / Heating

6: 84 percent / tetrahydrofuran / 0 °C

7: 97 percent / LiAlH₄, NiCl₂ / tetrahydrofuran / -78 to -35 deg C, 30 min then room temp., 2.5 h

With potassium hydroxide; lithium aluminium tetrahydride; oxalyl dichloride; camphor-10-sulfonic acid; dimethyl sulfoxide; triethylamine; nickel dichloride; In tetrahydrofuran; pyridine; methanol;