1H-Pyrrole-2,3-dicarboxylicacid,4-methyl-5-phenyl-,dimethylester(9CI)

Base Information

• Chemical Name: 1H-Pyrrole-2,3-dicarboxylicacid,4-methyl-5-phenyl-,dimethylester(9CI)
• CAS No.: 83756-15-4
• Molecular Formula: C15H15 N O4
• Molecular Weight: 273.288
• Mol file: 83756-15-4.mol

Synonyms:1H-Pyrrole-2,3-dicarboxylicacid, 4-methyl-5-phenyl-, dimethyl ester (9CI)

Chemical Property of 1H-Pyrrole-2,3-dicarboxylicacid,4-methyl-5-phenyl-,dimethylester(9CI)

Chemical Property:

Purity/Quality:

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Technology Process of 1H-Pyrrole-2,3-dicarboxylicacid,4-methyl-5-phenyl-,dimethylester(9CI)

There total 4 articles about 1H-Pyrrole-2,3-dicarboxylicacid,4-methyl-5-phenyl-,dimethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-phenylpropan-1-one O-acetyl oxime (133145-92-3) + dimethyl acetylenedicarboxylate (762-42-5) → dimethyl 4-methyl-5-phenyl-1H-pyrrole-2,3-dicarboxylate (83756-15-4)

Guidance literature:

With oxygen; copper(l) chloride; sodium sulfite; In dimethyl sulfoxide; at 120 ℃; for 12h;

DOI:10.1039/c3cc44896g

Reference yield: 82.0%

C15H17NO5 → dimethyl 4-methyl-5-phenyl-1H-pyrrole-2,3-dicarboxylate (83756-15-4)

Guidance literature:

With silver tetrafluoroborate; (triphenylphosphine)gold(I) chloride; In toluene; at 100 ℃; for 12h;

DOI:10.1039/c0cc04372a

Reference yield: 35.0%

2H-azirine-2,3-dicarboxylic acid dimethyl ester (16504-44-2) + [E]-1-morpholino-1-phenyl-1-propene (30085-70-2) → dimethyl 4-methyl-5-phenyl-1H-pyrrole-2,3-dicarboxylate (83756-15-4)

Guidance literature:

In chloroform; at 0 ℃; for 24h;

DOI:10.1039/c39820000784

upstream raw materials:

2H-azirine-2,3-dicarboxylic acid dimethyl ester

[E]-1-morpholino-1-phenyl-1-propene

1-phenylpropan-1-one O-acetyl oxime

dimethyl acetylenedicarboxylate