2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one

Base Information

Chemical Name:2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one
CAS No.:88058-66-6
Molecular Formula:C₁₄H₁₇NO₃
Molecular Weight:247.294
Hs Code.:2924299090
DSSTox Substance ID:DTXSID60390858
Mol file:88058-66-6.mol

Synonyms:88058-66-6;2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one;N-(7-methoxy-1-oxo-3,4-dihydro-2H-naphthalen-2-yl)propanamide;N-(7-Methoxy-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide;SCHEMBL7280376;DTXSID60390858;VRUWWWJHIKQWDV-UHFFFAOYSA-N;AKOS030255797;FT-0674056

Suppliers and Price of 2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one
1g
$ 1265.00

Medical Isotopes, Inc.
2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one
100 mg
$ 840.00

American Custom Chemicals Corporation
2-PROPANAMIDO-7-METHOXY-3,4-DIHYDRONAPHTHALEN-1-(2H)-ONE 95.00%
1G
$ 1963.50

American Custom Chemicals Corporation
2-PROPANAMIDO-7-METHOXY-3,4-DIHYDRONAPHTHALEN-1-(2H)-ONE 95.00%
100MG
$ 750.75

Total 7 raw suppliers

Chemical Property of 2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one

Chemical Property:

Melting Point:129-131°C
Boiling Point:486.4±45.0 °C(Predicted)
PKA:14.73±0.20(Predicted)
PSA：55.40000
Density:1.17±0.1 g/cm3(Predicted)
LogP:2.10980
Solubility.:Dichloromethane, Ethyl Acetate, Methanol
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:247.12084340
Heavy Atom Count:18
Complexity:329

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)NC1CCC2=C(C1=O)C=C(C=C2)OC
Uses 2-PropanaMido-7-Methoxy-3,4-dihydronaphthalen-1-(2H)-one is used in the synthesis of 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, a new class of dopamine agonists. Used in the synthesis of 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, a new class of dopamine agonists.

Technology Process of 2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one

There total 2 articles about 2-Propanamido-7-methoxy-3,4-dihydronaphthalen-1-(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6836-19-7
7-Methoxy-1-tetralone

: 88058-66-6
N-(7-Methoxy-1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butoxide, isoamyl nitrite / diethyl ether; butan-1-ol / 4 h / Ambient temperature

2: H₂ / 10percent Pd/C / tetrahydrofuran

With potassium tert-butylate; hydrogen; isopentyl nitrite; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; butan-1-ol;
DOI:10.1021/jm00378a014